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AGK7

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848978

AGK7 is an inactive control and an isomer of AGK2. AGK2 is a cell-permeable, selective inhibitor of SIRT2 which is a NAD+ (nicotinamide adenine dinucleotide) -dependent deacetylase (IC50 = 3.5 uM). AGK2 rescues alpha-synuclein toxicity in alpha-Syn-H4 cells… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
AGK7, Biochemical
Full Product Name
AGK7
Product Synonym Names
2-cyano-3-[5- (2; 5-dichlorophenyl) furan-2-yl]-N-quinolin-8-ylprop-2-enamide; SIRT2 Inhibitor (Inactive Control)
Form/Format
A crystalline solid
Purity/Purification
>=95%
Preparation and Storage
Store at -20 degree C
Shelf life: ~36 months
Molecular Weight
434.27
Solubility
~0.5 mg/ml in DMSO
~0.2 mg/ml in DMF
Molecular Formula
C??H??Cl?N?O?
CAS Number
304896-21-7
PubChem CID
1372572
SMILES
C1=CC2=C (C (=C1)NC (=O)C (=CC3=CC=C (O3)C4=C (C=CC (=C4)Cl)Cl)C#N)N=CC=C2
InChi
InChI=1S/C23H13Cl2N3O2/c24-16-6-8-19 (25)18 (12-16)21-9-7-17 (30-21)11-15 (13-26)23 (29)28-20-5-1-3-14-4-2-10-27-22 (14)20/h1-12H, (H,28,29)/b15-11+
InChi Key
WRDKBSLEHFRKGG-RVDMUPIBSA-N

Product Categories/Family for AGK7 biochemical

Biochemicals; Enzyme Inhibitors; SIRT Inhibitors; Biochemicals (A-Z); Neuroscience; Epigenetics; Eraser Enzymes; Sirtuins (SIRTs)

Structure of AGK7 biochemical

AGK7 Biochemical – Cat# MBS848978

Product References and Citations for AGK7 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/1372572

Other Notes

Small volumes of AGK7 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AGK7 purchase

MBS848978 is a biochemical targeting AGK7.
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