L002 ([ (3)

Name: L002 ([ (3); MyBioSource
Brand: MyBioSource
SKU: MBS848994
Price: 180 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848994

L002 is an inhibitor of p300 histone acetyltransferase (KAT3B). It shows an IC50 of 1.98 uM against p300 in vitro. It inhibits acetylation of histones, p53 and suppresses STAT3 activation. It is cytotoxic to breast cancer cell lines, especially those derived… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

L002, Biochemical

Full Product Name

L002

Product Synonym Names

[ (3; 5-dimethyl-4-oxocyclohexa-2; 5-dien-1-ylidene) amino] 4-methoxybenzenesulfonate; 4- (4-methoxyphenylsulfonyloxyimino)-2; 6-dimethylcyclohexa-2; 5-dienone; (3; 5-dimethyl-4-oxocyclohexa-2; 5-dien-1-ylidene) amino 4-methoxybenzene-1-sulfonate; (3; 5-dimethyl-4-oxocyclohexa-2; 5-dienylidene) azamethyl 4-methoxybenzenesulfonate; 2; 6-dimethyl-2; 5-cyclohexadiene-1; 4-dione 4-[O-[ (4-methoxyphenyl) sulfonyl]oxime]; NSC764414; p300/CBP Inhibitor VI

Form/Format

A crystalline solid

Purity/Purification

>=98%

Preparation and Storage

Store at -20 degree C
Shelf life: ~36 months

Molecular Weight

321.35

Solubility

~1 mg/ml in Ethanol
~30 mg/ml in DMSO and DMF

Molecular Formula

C??H??NO?S

CAS Number

321695-57-2

PubChem CID

2221149

SMILES

CC1=CC (=NOS (=O)(=O)C2=CC=C (C=C2)OC)C=C (C1=O)C

InChi

InChI=1S/C15H15NO5S/c1-10-8-12 (9-11 (2)15 (10)17)16-21-22 (18,19)14-6-4-13 (20-3)5-7-14/h4-9H,1-3H3

InChi Key

VEWFTYOFWIXCIO-UHFFFAOYSA-N

Product Categories/Family for L002 biochemical

Biochemicals; Biochemicals (A-Z); Enzyme Inhibitors; Histone Acetyltransferase (HAT) Inhibitors; Epigenetics; Cancer Research; Epigenetic Regulation; Writer Enzymes

Product References and Citations for L002 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/2221149

Other Notes

Small volumes of L002 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for L002 purchase

MBS848994 is a biochemical targeting L002.