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RTA 408 (N-[ (4aS)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848995

RTA 408 is a synthetic oleanane triterpenoid that activates Nrf2. RTA 408 activates Nrf2 and suppresses nitric oxide and pro-inflammatory cytokine levels in interferon-gamma-stimulated RAW 264.7 macrophage cells at low concentrations ( More details

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Product Overview

Product Name
RTA 408, Biochemical
Full Product Name
RTA 408
Product Synonym Names
N-[ (4aS; 6aR; 6bS; 8aR; 12aS; 14aR; 14bS)-11-cyano-2; 2; 6a; 6b; 9; 9; 12a-heptamethyl-10; 14-dioxo-1; 3; 4; 5; 6; 7; 8; 8a; 14a; 14b-decahydropicen-4a-yl]-2; 2-difluoropropanamide; Omaveloxolone; N- (2-cyano-3; 12-dioxo-28-noroleana-1; 9 (11)-dien-17-yl)-2; 2-difluoropropanamide; N- ( (4aS; 6aR; 6bS; 8aR; 12aS; 14aR; 14bS)-11-cyano-2; 2; 6a; 6b; 9; 9; 12a-heptamethyl-10; 14-dioxo-1; 2; 3; 4; 4a; 5; 6; 6a; 6b; 7; 8; 8a; 9; 10; 12a; 14; 14a; 14b-octadecahydropicen-4a-yl)-2; 2-difluoropropanamide
Form/Format
A crystalline solid
Purity/Purification
>=98%
Preparation and Storage
Store at -20 degree C
Shelf life: ~36 months
Molecular Weight
554.71
Solubility
~2 mg/ml in ethanol
DMSO and DMF
Molecular Formula
C??H??F?N?O?
CAS Number
1474034-05-3
PubChem CID
71811910
SMILES
CC1 (CCC2 (CCC3 (C (C2C1)C (=O)C=C4C3 (CCC5C4 (C=C (C (=O)C5 (C)C)C#N)C)C)C)NC (=O)C (C)(F)F)C
InChi
InChI=1S/C33H44F2N2O3/c1-27 (2)11-13-33 (37-26 (40)32 (8,34)35)14-12-31 (7)24 (20 (33)17-27)21 (38)15-23-29 (5)16-19 (18-36)25 (39)28 (3,4)22 (29)9-10-30 (23,31)6/h15-16,20,22,24H,9-14,17H2,1-8H3, (H,37,40)/t20-,22-,24-,29-,30+,31+,33-/m0/s1
InChi Key
RJCWBNBKOKFWNY-IDPLTSGASA-N

Structure of RTA 408 biochemical

RTA 408 N-[ (4aS Biochemical – Cat# MBS848995

Product References and Citations for RTA 408 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/71811910

Other Notes

Small volumes of RTA 408 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RTA 408 purchase

MBS848995 is a biochemical targeting RTA 408.
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