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ZM306416

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS849010

ZM 306416 is an inhibitor of vascular endothelial growth factor (VEGF) receptor tyrosine kinase. It inhibits the activity of KDR and Flt VEGF receptors with IC50 values of 100 nM and 2 uM, respectively. It is also a potent inhibitor of EGFR with an IC50 value… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
ZM306416, Biochemical
Full Product Name
ZM306416
Product Synonym Names
N- (4-chloro-2-fluorophenyl)-6; 7-dimethoxyquinazolin-4-amine; 4-[ (4'-Chloro-2'-fluoro) phenylamino]-6; 7-dimethoxyquinazoline; CB-676475
Form/Format
A crystalline solid
Purity/Purification
>=98%
Preparation and Storage
Store at -20 degree C
Shelf life: ~36 months
Molecular Weight
333.74
Solubility
~20 mg/ml in Ethanol
~50 mg/ml in DMSO and DMF
Molecular Formula
C??H??ClFN?O?
CAS Number
690206-97-4
MDL Number
MFCD02683969
PubChem CID
5329006
SMILES
COC1=C (C=C2C (=C1)C (=NC=N2)NC3=C (C=C (C=C3)Cl)F)OC
InChi
InChI=1S/C16H13ClFN3O2/c1-22-14-6-10-13 (7-15 (14)23-2)19-8-20-16 (10)21-12-4-3-9 (17)5-11 (12)18/h3-8H,1-2H3, (H,19,20,21)
InChi Key
YHUIUSRCUKUUQA-UHFFFAOYSA-N

Product Categories/Family for ZM306416 biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Kinase Inhibitors  (A-Z); Cancer Research; Oncogenic Signaling Pathway; Signaling Pathways; EGFR Signaling; EGFR Inhibitors; Biochemicals (A-Z); Signal Transduction; Protein Kinases; Protein Tyrosine K

Structure of ZM306416 biochemical

ZM306416 Biochemical – Cat# MBS849010

Product References and Citations for ZM306416 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/5329006

Other Notes

Small volumes of ZM306416 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ZM306416 purchase

MBS849010 is a biochemical targeting ZM306416.
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