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Nek2/Hec1 inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS849019

Nek2/Hec1 inhibitor targets the Hec1/Nek2 pathway and causes chromosome mis-alignment as well as cell death. The IC50 for cytotoxicity in MDA-MB231, MDA-MB468, HeLa and K562 cell lines is 1.1 uM, 3.4 uM,1.6 uM and 1.2 uM respectively. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Nek2/Hec1, Biochemical
Full Product Name
Nek2/Hec1 inhibitor
Product Synonym Names
N-[4- (2; 4-Dimethylphenyl)-2-thiazolyl]-4-pyridinecarboxamide; N-[4- (2; 4-Dimethylphenyl) thiazol-2-yl]isonicotinamide
Form/Format
Solid
Purity/Purification
0.97
Preparation and Storage
Store at -20 degree C
Shelf life: ~36 months
Molecular Weight
309.39
Solubility
Soluble in DMSO
Molecular Formula
C??H??N?OS
CAS Number
560103-80-2
MDL Number
MFCD03384899
PubChem CID
4363180
SMILES
O=C (C1=CC=NC=C1)NC2=NC (C3=CC=C (C)C=C3C)=CS2
InChi
InChI=1S/C17H15N3OS/c1-11-3-4-14 (12 (2)9-11)15-10-22-17 (19-15)20-16 (21)13-5-7-18-8-6-13/h3-10H,1-2H3, (H,19,20,21)
InChi Key
IBQLKKBLBXJSGU-UHFFFAOYSA-N

Product Categories/Family for Nek2/Hec1 biochemical

Biochemicals; Biochemicals (A-Z); Anticancer Agents; Enzyme Inhibitors; Microtubule Inhibitors

Structure of Nek2/Hec1 biochemical

Nek2/Hec1 inhibitor Biochemical – Cat# MBS849019

Product References and Citations for Nek2/Hec1 biochemical

https://pubchem.ncbi.nlm.nih.gov/substance/385835576

Other Notes

Small volumes of Nek2/Hec1 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Nek2/Hec1 purchase

MBS849019 is a biochemical targeting Nek2/Hec1. Also known as Nek2/Hec1 inhibitor.
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