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K-604, ACAT-1 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS849021

K-604 is an inhibitor of acyl-CoA:cholesterol acyltransferase 1 (ACAT1). The IC50 values of K-604 for human ACAT-1 and ACAT-2 are 0.45 uM and 102.85 uM respectively, showing that K-604 is 229-fold more selective for ACAT-1. It suppresses the development of… More details

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Product Overview

Product Name
K-604, ACAT-1, Biochemical
Full Product Name
K-604, ACAT-1 Inhibitor
Product Synonym Names
2- (4- (2- (1H-benzo[d]imidazol-2-ylthio) ethyl) piperazin-1-yl)-N- (6-methyl-2; 4-bis (methylthio) pyridin-3-yl) acetamide; 4-[2- (1H-Benzimidazol-2-ylthio) ethyl]-N-[6-methyl-2; 4-bis (methylthio)-3-pyridinyl]-1-piperazineacetamide
Form/Format
Solid
Purity/Purification
0.95
Preparation and Storage
Store at -20 degree C
Shelf life: ~36 months
Molecular Weight
502.72
Solubility
Soluble in DMSO
Molecular Formula
C??H??N?OS?
CAS Number
561023-90-3
PubChem CID
9892288
SMILES
CC1=CC (=C (C (=N1)SC)NC (=O)CN2CCN (CC2)CCSC3=NC4=CC=CC=C4N3)SC
InChi
InChI=1S/C23H30N6OS3/c1-16-14-19 (31-2)21 (22 (24-16)32-3)27-20 (30)15-29-10-8-28 (9-11-29)12-13-33-23-25-17-6-4-5-7-18 (17)26-23/h4-7,14H,8-13,15H2,1-3H3, (H,25,26)(H,27,30)
InChi Key
VGGMTOYKEDKFLN-UHFFFAOYSA-N

Product Categories/Family for K-604, ACAT-1 biochemical

Biochemicals; Enzyme Inhibitors; ACAT Inhibitors; Biochemicals; Biochemicals (A-Z); Diabetes; Obesity & Metabolic Syndrome; Lipids Metabolism; Proteins; Enzymes; ACAT (Acyl; CoA cholesteryl acyl transferase); Enzyme Inhibitors (A-Z)

Structure of K-604, ACAT-1 biochemical

K-604, ACAT-1 Inhibitor Biochemical – Cat# MBS849021

Product References and Citations for K-604, ACAT-1 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/9892288

Other Notes

Small volumes of K-604, ACAT-1 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for K-604, ACAT-1 purchase

MBS849021 is a biochemical targeting K-604, ACAT-1. Also known as K-604, ACAT-1 Inhibitor.
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