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WAY-265497

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS849031

WAY-265497 is a potent ATP-binding site-targeting inhibitor of Cdk4/D1 kinase activity with an IC50 of 30 nM. It inhibits HCT116 and MCF-7 cancer cells with IC50 values of 0.73 and 0.88 uM, respectively. It inhibits Cdk2/E and Cdk1/B at higher concentrations… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
WAY-265497, Biochemical
Full Product Name
WAY-265497
Product Synonym Names
4-[[[ (4-Hydroxy-5-propoxy-2-pyridinyl) methyl]amino]methylene]-6-iodo-1; 3 (2H; 4H)-isoquinolinedione; Cdk4 Inhibitor V
Form/Format
Solid
Purity/Purification
0.95
Preparation and Storage
Store at -20 degree C
Shelf life: ~36 months
Molecular Weight
479.27
Solubility
50 mg/ml in DMSO
Molecular Formula
C??H??IN?O?
CAS Number
943746-57-4
SMILES
O=C1NC (/C (C2=C1C=CC (I)=C2)=C\NCC3=NC=C (OCCC)C (O)=C3)=O
InChi
InChI=1S/C19H18IN3O4/c1-2-5-27-17-10-22-12 (7-16 (17)24)8-21-9-15-14-6-11 (20)3-4-13 (14)18 (25)23-19 (15)26/h3-4,6-7,9-10,21H,2,5,8H2,1H3, (H,22,24)(H,23,25,26)/b15-9-
InChi Key
DXMZEMWEDCPBNA-DHDCSXOGSA-N

Product Categories/Family for WAY-265497 biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Kinase Inhibitors  (A-Z); Biochemicals; Biochemicals (A-Z); Protein Tyrosine Kinase Inhibitors; Enzyme Inhibitors (A-Z)

Structure of WAY-265497 biochemical

WAY-265497 Biochemical – Cat# MBS849031

Other Notes

Small volumes of WAY-265497 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for WAY-265497 purchase

MBS849031 is a biochemical targeting WAY-265497.
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