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ONC212

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS849045

ONC212 is a fluorinated imipridone analogue of ONC201. It is an activator of GPCR GPR132 and Galphaq signaling, which functions as a tumor suppressor. It induces apoptosis in HPAF-II and AsPC1 cell lines at 20 uM and potently prevents colony formation at 5 uM… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
ONC212, Biochemical
Full Product Name
ONC212
Product Synonym Names
11-benzyl-7-[[4- (trifluoromethyl) phenyl]methyl]-2; 5; 7; 11-tetrazatricyclo[7.4.0.02; 6]trideca-1 (9); 5-dien-8-one
Form/Format
Solid
Purity/Purification
0.992
Preparation and Storage
Store at -20 degree C
Shelf life: ~36 months
Molecular Weight
440.46
Solubility
50 mg/ml in DMSO (need ultrasonication)
Molecular Formula
C??H??F?N?O
CAS Number
1807861-48-8
PubChem CID
124085867
SMILES
C1CN (CC2=C1N3CCN=C3N (C2=O)CC4=CC=C (C=C4)C (F)(F)F)CC5=CC=CC=C5
InChi
InChI=1S/C24H23F3N4O/c25-24 (26,27)19-8-6-18 (7-9-19)15-31-22 (32)20-16-29 (14-17-4-2-1-3-5-17)12-10-21 (20)30-13-11-28-23 (30)31/h1-9H,10-16H2
InChi Key
DFULPGUTXZTYKA-UHFFFAOYSA-N

Product Categories/Family for ONC212 biochemical

Biochemicals; Biochemicals (A-Z); Anticancer Agents; Cancer Research

Structure of ONC212 biochemical

ONC212 Biochemical – Cat# MBS849045

Product References and Citations for ONC212 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/124085867

Other Notes

Small volumes of ONC212 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ONC212 purchase

MBS849045 is a biochemical targeting ONC212.
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