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A-839977 (1- (2)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS849068

A-839977 is a potent antagonist of the purinergic receptor P2X subtype 7 (P2X7). A-839977 potently blocks BzATP-induced calcium influx at recombinant human, rat and mouse P2X7 receptors with IC50 values of 20 nM, 42 nM and 150 nM respectively. It also… More details

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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Product Overview

Product Name
A-839977, Biochemical
Full Product Name
A-839977
Product Synonym Names
1- (2; 3-dichlorophenyl)-N-[ (2-pyridin-2-yloxyphenyl) methyl]tetrazol-5-amine
Form/Format
Solid
Purity/Purification
0.98
Preparation and Storage
Store at -20 degree C
Shelf life: ~36 months
Molecular Weight
413.26
Solubility
Soluble in DMSO
Molecular Formula
C??H??Cl?N?O
CAS Number
870061-27-1
MDL Number
MFCD19690959
PubChem CID
53325875
SMILES
C1=CC=C (C (=C1)CNC2=NN=NN2C3=C (C (=CC=C3)Cl)Cl)OC4=CC=CC=N4
InChi
InChI=1S/C19H14Cl2N6O/c20-14-7-5-8-15 (18 (14)21)27-19 (24-25-26-27)23-12-13-6-1-2-9-16 (13)28-17-10-3-4-11-22-17/h1-11H,12H2, (H,23,24,26)
InChi Key
GMVNBKZQJFRFAR-UHFFFAOYSA-N

Structure of A-839977 biochemical

A-839977 1- (2 Biochemical – Cat# MBS849068

Product References and Citations for A-839977 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/53325875

Other Notes

Small volumes of A-839977 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for A-839977 purchase

MBS849068 is a biochemical targeting A-839977.
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