Human Cellexp DLL1 Active Protein – Cat# MBS849790

DLL1 Human Cellexp Active Protein

Name: DLL1 Active Protein; Human Cellexp; MyBioSource
Brand: MyBioSource
SKU: MBS849790
Price: 275 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS849790

The Notch ligand delta-like protein 1 (DLL1) is essential for postnatal arteriogenesis and contributes to tumor progression. DLL1 is involved in differentiation and self-renewal of adipocyte stem cells. Blocks the differentiation of progenitor cells into the… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

DLL1, Active Protein

Full Product Name

Human CellExp DLL1, Mouse Recombinant

Product Gene Name

Dll1 active protein

Product Synonym Names

Delta-like Protein 1; Delta 1

Host

HEK293 cells

Form/Format

Lyophilized powder. Lyophilized from 0.2 um-filtered PBS

Purity/Purification

>90% by SDS-PAGE

Preparation and Storage

Store at -20 degree C
Centrifuge the vial prior to opening.
Shelf life: ~12 months

Molecular Weight

78,449 Da

3D Structure

ModBase 3D Structure for Q61483

Active Protein Note

Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.

Gene Source

Mouse

Endotoxin

<1.0 EU per/ug

Biological Activity

Measured by inhibition of adipogenesis of 3T3L-1 cells and induction of Hes-1 in 3T3L-1 cells

Product Categories/Family for Dll1 active protein

Cytokines; Growth Factors & Hormones; Human cell expressed recombinant proteins; Proteins; Enzymes; Human cell expressed recombinant proteins Cytokines; BAFFs; Cytokines & Growth Factors (A-Z); Proteins & Enzymes (A-Z); Signaling Pathways; TNF Signaling P

Other Notes

Small volumes of Dll1 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Dll1 purchase

MBS849790 is an active protein targeting Dll1. Also known as Human CellExp DLL1, Mouse Recombinant. Host: HEK293 cells.

Additional Details

NCBI/Uniprot data below describe general gene information for Dll1. It may not necessarily be applicable to this product.

NCBI GI #

40789272

NCBI GeneID

13388

NCBI Accession #

NP_031891.2

UniProt Primary Accession #

Q61483

UniProt Secondary Accession #

Q6PFV7

UniProt Related Accession #

Q61483

GenBank Nucleotide #

NM_007865.3

NCBI Official Full Name

delta-like protein 1

NCBI Official Synonym Full Names

delta-like 1 (Drosophila)

NCBI Official Symbol

Dll1

NCBI Official Synonym Symbols

Delta1

UniProt Protein Name

Delta-like protein 1

UniProt Synonym Protein Names

Drosophila Delta homolog 1; Delta1

Protein Family

Delta-like protein

UniProt Gene Name

Dll1

UniProt Synonym Gene Names

Delta1

UniProt Entry Name

DLL1_MOUSE

NCBI Protein Information

delta-like protein 1; delta like-1; drosophila Delta homolog 1

UniProt Comments for Dll1

DLL1: Acts as a ligand for Notch receptors. Blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor. Interacts with Notch receptors. Expressed in heart and pancreas, with lower expression in brain and muscle and almost no expression in placenta, lung, liver and kidney.

Protein type: Cell development/differentiation; Membrane protein, integral; Motility/polarity/chemotaxis

Cellular Component: membrane; plasma membrane; integral to membrane; cytoplasmic vesicle

Molecular Function: protein binding; calcium ion binding; Notch binding

Biological Process: nervous system development; somitogenesis; Notch signaling pathway; inner ear morphogenesis; negative regulation of myeloid cell differentiation; negative regulation of interleukin-10 production; in utero embryonic development; multicellular organismal development; auditory receptor cell differentiation; odontogenesis of dentine-containing teeth; compartment specification; negative regulation of cell differentiation; somite specification; organ morphogenesis; negative regulation of neuron differentiation; regulation of neurogenesis; cell-cell signaling; negative regulation of auditory receptor cell differentiation; positive regulation of transcription from RNA polymerase II promoter; cell communication; heart looping; determination of left/right symmetry; cell differentiation; auditory receptor cell fate commitment; inner ear development; positive regulation of Notch signaling pathway

Research Articles on Dll1

1. Spatiotemporal expression oscillations of Notch1 and Dll1 are coordinated across the mouse pre-somitic mesoderm.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Dll1 active protein

Reference Product	PubMed Publications
Notch1 active protein	>107 publications with Dll1 and Notch1
Dll4 active protein	>65 publications with Dll1 and Dll4
Notch2 active protein	>38 publications with Dll1 and Notch2
Jag1 active protein	>34 publications with Dll1 and Jag1
Hes5 active protein	>25 publications with Dll1 and Hes5
Notch3 active protein	>16 publications with Dll1 and Notch3
Adam10 active protein	>3 publications with Dll1 and Adam10
Psen1 active protein	>3 publications with Dll1 and Psen1

Pathways associated with Dll1 active protein

Products by Pathway	Pathway Diagram
Activated NOTCH1 Transmits Signal To The Nucleus Pathway antibodies	Activated NOTCH1 Transmits Signal To The Nucleus Pathway Diagram
Constitutive Signaling By NOTCH1 HD Domain Mutants Pathway antibodies	Constitutive Signaling By NOTCH1 HD Domain Mutants Pathway Diagram
Constitutive Signaling By NOTCH1 HD+PEST Domain Mutants Pathway antibodies	Constitutive Signaling By NOTCH1 HD+PEST Domain Mutants Pathway Diagram
Constitutive Signaling By NOTCH1 PEST Domain Mutants Pathway antibodies	Constitutive Signaling By NOTCH1 PEST Domain Mutants Pathway Diagram
Constitutive Signaling By NOTCH1 T(7;9)(NOTCH1:M1580_K2555) Translocation Mutant Pathway antibodies	Constitutive Signaling By NOTCH1 T(7;9)(NOTCH1:M1580_K2555) Translocation Mutant Pathway Diagram
Delta-Notch Signaling Pathway antibodies	Delta-Notch Signaling Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
FBXW7 Mutants And NOTCH1 In Cancer Pathway antibodies	FBXW7 Mutants And NOTCH1 In Cancer Pathway Diagram
NOTCH2 Activation And Transmission Of Signal To The Nucleus Pathway antibodies	NOTCH2 Activation And Transmission Of Signal To The Nucleus Pathway Diagram
Notch Signaling Pathway antibodies	Notch Signaling Pathway Diagram

Diseases associated with Dll1 active protein

Disease Name	Pubmed Publications
Congenital Abnormalities Antibodies	>11 publications with Dll1 and Congenital Abnormalities
Inflammation Antibodies	>9 publications with Dll1 and Inflammation
Disease Models, Animal Antibodies	>9 publications with Dll1 and Disease Models, Animal
Carcinoma Antibodies	>9 publications with Dll1 and Carcinoma
Nervous System Diseases Antibodies	>8 publications with Dll1 and Nervous System Diseases
Necrosis Antibodies	>5 publications with Dll1 and Necrosis
Abnormalities, Multiple Antibodies	>5 publications with Dll1 and Abnormalities, Multiple
Carcinoma, Squamous Cell Antibodies	>4 publications with Dll1 and Carcinoma, Squamous Cell
Lung Diseases Antibodies	>4 publications with Dll1 and Lung Diseases
Hyperplasia Antibodies	>3 publications with Dll1 and Hyperplasia

Organs/Tissues associated with Dll1 active protein

Organ/Tissue Name	Pubmed Publications
Embryonic Tissue Antibodies	>41 publications with Dll1 and Embryonic Tissue
Brain Antibodies	>37 publications with Dll1 and Brain
Lung Antibodies	>15 publications with Dll1 and Lung
Spinal Cord Antibodies	>11 publications with Dll1 and Spinal Cord
Pancreas Antibodies	>8 publications with Dll1 and Pancreas
Kidney Antibodies	>7 publications with Dll1 and Kidney
Eye Antibodies	>6 publications with Dll1 and Eye
Inner Ear Antibodies	>5 publications with Dll1 and Inner Ear
Lymph Node Antibodies	>3 publications with Dll1 and Lymph Node
Dorsal Root Ganglion Antibodies	>2 publications with Dll1 and Dorsal Root Ganglion