• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Fatty Acid Amide Hyrdrolase 1 (FAAH1) Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS849884

Fatty acid amide Hydrolase 1 (FAAH1) is an integral membrane enzyme that hydrolyzes endocannabinoid anandamide, related signaling lipids, bioactive fatty acid amides. Inactivation of FAAH1 produces analgesic, anti-inflammatory, anxioloytic and antidepressant… More details

DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Product Name
Fatty Acid Amide Hyrdrolase 1 (FAAH1), Active Protein
Full Product Name
Fatty Acid Amide Hyrdrolase 1 (FAAH1), Active, Human Recombinant
Product Gene Name
FAAH1 active protein
Product Synonym Names
Anandamide amidohydrolase 1; Oleamide hydrolase 1
Host
E Coli
Form/Format
Lyophilized. Proprietary buffer
Preparation and Storage
Store at -20 degree C
Centrifuge the vial prior to opening.
Shelf life: ~12 months
Molecular Weight
579
OMIM
gene 606581
3D Structure
ModBase 3D Structure for O00519
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Gene Source
Human
Biological Activity
Specific activity >= 9 mU/mg.
Measure by its abilility to hydrolyze 1.0 umole of AMC Arachidonyl Amide at pH 7.4 and 37 degree C.
Reconstitution Instruction
Reconstitute in distilled water.

Product Categories/Family for FAAH1 active protein

Cytokines; Growth Factors & Hormones; Human cell expressed recombinant proteins; Proteins; Enzymes; Human cell expressed recombinant proteins Cytokines; BAFFs; Cytokines & Growth Factors (A-Z); Proteins & Enzymes (A-Z); Signaling Pathways; TNF Signaling P

SDS-Page of FAAH1 active protein

FAAH1 Active Protein – Cat# MBS849884

Testing Data of FAAH1 active protein

FAAH1 Active Protein, Testing Data – Cat# MBS849884

Testing Data of FAAH1 active protein

FAAH1 Active Protein, Testing Data – Cat# MBS849884

Other Notes

Small volumes of FAAH1 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FAAH1 purchase

MBS849884 is an active protein targeting FAAH1. Also known as Fatty Acid Amide Hyrdrolase 1 (FAAH1), Active, Human Recombinant. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for FAAH1. It may not necessarily be applicable to this product.

NCBI GI #
60416391
NCBI GeneID
2166
NCBI Accession #
O00519.2
UniProt Primary Accession #
O00519
UniProt Secondary Accession #
Q52M86; Q5TDF8; D3DQ19
UniProt Related Accession #
O00519
NCBI Official Full Name
Fatty-acid amide hydrolase 1
NCBI Official Synonym Full Names
fatty acid amide hydrolase
NCBI Official Symbol
FAAH
NCBI Official Synonym Symbols
PSAB; FAAH-1
UniProt Protein Name
Fatty-acid amide hydrolase 1
UniProt Synonym Protein Names
Anandamide amidohydrolase 1; Oleamide hydrolase 1
UniProt Gene Name
FAAH
UniProt Synonym Gene Names
FAAH1
UniProt Entry Name
FAAH1_HUMAN
NCBI Protein Information
fatty-acid amide hydrolase 1; oleamide hydrolase 1; anandamide amidohydrolase 1

NCBI Summary for FAAH1

This gene encodes a protein that is responsible for the hydrolysis of a number of primary and secondary fatty acid amides, including the neuromodulatory compounds anandamide and oleamide. [provided by RefSeq, Jul 2008]

UniProt Comments for FAAH1

FAAH: Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes polyunsaturated substrate anandamide preferentially as compared to monounsaturated substrates. Homodimer. Highly expressed in the brain, small intestine, pancreas, skeletal muscle and testis. Also expressed in the kidney, liver, lung, placenta and prostate. Inhibited by O-aryl carbamates and alpha-keto heterocytes. Belongs to the amidase family.

Protein type: EC 3.5.1.99; Membrane protein, integral; Hydrolase

Chromosomal Location of Human Ortholog: 1p35-p34

Cellular Component: cytoskeleton; cytoplasm; integral to membrane; endomembrane system

Molecular Function: fatty acid amide hydrolase activity; carbon-nitrogen ligase activity, with glutamine as amido-N-donor; acylglycerol lipase activity

Biological Process: fatty acid catabolic process

Disease: Polysubstance Abuse, Susceptibility To
Show more

Research Articles on FAAH1

1. In subcutaneous adipose tissue, DAGL-a mRNA was upregulated and fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) mRNAs were down-regulated in obese subjects, but the diets had no influence.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with FAAH1 active protein

 Reference Product  PubMed Publications
 TRPV1 active protein  >93 publications with FAAH1 and TRPV1
 CNR1 active protein  >40 publications with FAAH1 and CNR1
 CNR2 active protein  >16 publications with FAAH1 and CNR2
 MGLL active protein  >9 publications with FAAH1 and MGLL
 FABP5 active protein  >4 publications with FAAH1 and FABP5
 NAPEPLD active protein  >3 publications with FAAH1 and NAPEPLD
 FABP7 active protein  >3 publications with FAAH1 and FABP7
 FABP3 active protein  >2 publications with FAAH1 and FABP3
 LEP active protein  >1 publications with FAAH1 and LEP

Pathways associated with FAAH1 active protein

 Products by Pathway  Pathway Diagram
 Retrograde Endocannabinoid Signaling Pathway antibodies  Retrograde Endocannabinoid Signaling Pathway Diagram
 Retrograde Endocannabinoid Signaling Pathway antibodies  Retrograde Endocannabinoid Signaling Pathway Diagram
 Anandamide Degradation Pathway antibodies  Anandamide Degradation Pathway Diagram
 Anandamide Degradation Pathway antibodies  Anandamide Degradation Pathway Diagram

Diseases associated with FAAH1 active protein

 Disease Name  Pubmed Publications
 Pain Antibodies  >196 publications with FAAH1 and Pain
 Nervous System Diseases Antibodies  >150 publications with FAAH1 and Nervous System Diseases
 Inflammation Antibodies  >92 publications with FAAH1 and Inflammation
 Mental Disorders Antibodies  >89 publications with FAAH1 and Mental Disorders
 Obesity Antibodies  >53 publications with FAAH1 and Obesity
 Fatty Liver Antibodies  >52 publications with FAAH1 and Fatty Liver
 Substance-Related Disorders Antibodies  >46 publications with FAAH1 and Substance-Related Disorders
 Brain Diseases Antibodies  >44 publications with FAAH1 and Brain Diseases
 Death Antibodies  >22 publications with FAAH1 and Death
 Necrosis Antibodies  >19 publications with FAAH1 and Necrosis

Organs/Tissues associated with FAAH1 active protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >398 publications with FAAH1 and Brain
 Nerve Antibodies  >49 publications with FAAH1 and Nerve
 Muscle Antibodies  >32 publications with FAAH1 and Muscle
 Intestine Antibodies  >30 publications with FAAH1 and Intestine
 Adipose Tissue Antibodies  >25 publications with FAAH1 and Adipose Tissue
 Connective Tissue Antibodies  >20 publications with FAAH1 and Connective Tissue
 Eye Antibodies  >19 publications with FAAH1 and Eye
 Placenta Antibodies  >15 publications with FAAH1 and Placenta
 Lung Antibodies  >14 publications with FAAH1 and Lung
 Kidney Antibodies  >12 publications with FAAH1 and Kidney
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000