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Yeast Kex-2 Protein (MUC16) Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS849904

Cancer Antigen 125 (CA125) is a surface antigen associated with epithelial ovarian cancer. In serum, CA125 is associated with a high molecular weight glycoprotein. Published studies have indicated that elevated serum CA125 levels can be found in individuals… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Yeast Kex-2 Protein (MUC16), Active Protein
Full Product Name
Yeast Kex-2 Recombinant Protein
Product Gene Name
Product Synonym Names
MUCIN 16; muc16; CA-125; Carbohydrate Antigen 125; Mucin-16
Sequence
LPVPAPPMDS SLLPVKEAED KLSINDPLFE RQWHLVNPSF PGSDINVLDL WYNNITGAGV VaaIVDDGLD YENEDLKDNF CAEGSWDFND NTNLPKPRLS DDYHGTRCAG EIAAKKGNNF CGVGVGYNAK ISGIRILSGD ITTEDEAASL IYGLDVNDIY SCSWGPADDG RHLQGPSDLV KKALVKGVTE GRDSKGAIYV FASGNGGTRG DNCNYDGYTN SIYSITIGAI DHKDLHPPYS EGCSAVMAVT YSSGSGEYIH SSDINGRCSN SHGGTSAaaP LAAGVYTLLL EANPNLTWRD VQYLSILSAV GLEKNADGDW RDSAMGKKYS HRYGFGKIDA HKLIEMSKTW ENVNAQTWFY LPTLYVSQST NSTEETLESV ITISEKSLQD ANFKRIEHVT VTVDIDTEIR GTTTVDLISP AGIISNLGVV RPRDVSSEGF KDWTFMSVAH WGENGVGDWK IKVKTTENGH RIDFHSWRLK LFGESIDSSK TETFVFGNDK EEVEPAATES TVSQYSASST SISISATSTS SISIGVETSA IPQTTTASTD PDSDPNTP
Host
Hi-5 Insect cells (BTI-Tn-5B1-4)
Form/Format
Lyophilized powder
Purity/Purification
>= 95% by SDS-PAGE and HPLC
Preparation and Storage
Store at -20 degree C
Centrifuge the vial prior to opening.
Shelf life: ~12 months
Molecular Weight
90,003 Da
Chromosome Location
Chromosome: XIV; NC_001146.8 (202428..204872). Location: chromosome: XIV
3D Structure
ModBase 3D Structure for P13134
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Gene Source
Saccharomyces cerevisiae
Biological Activity
Specific activity >100 kU/mL (EIA)

Other Notes

Small volumes of MUC16 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MUC16 purchase

MBS849904 is an active protein targeting MUC16. Also known as Yeast Kex-2 Recombinant Protein. Host: Hi-5 Insect cells (BTI-Tn-5B1-4).

Additional Details

NCBI/Uniprot data below describe general gene information for MUC16. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
Kex2p
NCBI Official Symbol
KEX2
NCBI Official Synonym Symbols
QDS1; SRB1; VMA45
UniProt Protein Name
Kexin
UniProt Synonym Protein Names
Protease KEX2; Proteinase YSCF
Protein Family
UniProt Gene Name
KEX2
UniProt Synonym Gene Names
QDS1
UniProt Entry Name
KEX2_YEAST
NCBI Protein Information
Kex2p

UniProt Comments for MUC16

Function: Processing of precursors of alpha-factors and killer toxin.

Catalytic activity: Cleavage of -Lys-Arg-|-Xaa- and -Arg-Arg-|-Xaa- bonds to process yeast alpha-factor pheromone and killer toxin precursors.

Cofactor: Binds 3 calcium ions per subunit.

Subcellular location: Golgi apparatus › trans-Golgi network membrane; Single-pass type I membrane protein.

Post-translational modification: O-glycosylated.

Sequence similarities: Belongs to the peptidase S8 family. Furin subfamily.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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