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CD244/ 2b4/ SLAMF4 (CD244) Human Cellexp Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS849929

Natural killer cell receptor 2B4 is also known as NK cell type I receptor protein 2B4 (NKR2B4 or h2B4), SLAM family member 4 (SLAMF4), Signaling lymphocytic activation molecule 4, CD antigen CD244. NKR2B4/CD244 contain two Ig-like (immunoglobulin-like)… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
CD244/ 2B4/ SLAMF4, Active Protein
Full Product Name
Human CellExp CD244/ 2B4/ SLAMF4, Fc Tag, Human Recombinant
Product Gene Name
Product Synonym Names
CD244; 2B4; SLAMF4; NKR2B4; NAIL; h2B4
Host
HEK293 cells
Form/Format
Lyophilized from 0.22 um filtered solution in 50mM Tris, 100mM Glycine, pH7.5. Normally trehalose is added as protectant before lyophilization.
Purity/Purification
>=95% by SDS-PAGE
Preparation and Storage
Store at -20 degree C
Centrifuge the vial prior to opening.
Shelf life: ~12 months
Molecular Weight
370
OMIM
605554
3D Structure
ModBase 3D Structure for Q9BZW8
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Gene Source
Human
Endotoxin
<1 EU/ug by LAL method
Biological Activity
Immobilized Human CD48, His Tag at 5 ug/mL (100 uL/well) can bind Human 2B4, Fc Tag with a linear range of 0.313-5 ug/mL.
Measured by its binding ability in a functional ELISA.
Reconstitution Instruction
Reconstitute in sterile deionized water to a concentration of 50 ug/ml.

Testing Data of CD244 active protein

Human Cellexp CD244 Active Protein, Testing Data – Cat# MBS849929

Other Notes

Small volumes of CD244 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD244 purchase

MBS849929 is an active protein targeting CD244. Also known as Human CellExp CD244/ 2B4/ SLAMF4, Fc Tag, Human Recombinant. Host: HEK293 cells.

Additional Details

NCBI/Uniprot data below describe general gene information for CD244. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Natural killer cell receptor 2B4
NCBI Official Synonym Full Names
CD244 molecule, natural killer cell receptor 2B4
NCBI Official Symbol
CD244
NCBI Official Synonym Symbols
2B4; NAIL; Nmrk; NKR2B4; SLAMF4
UniProt Protein Name
Natural killer cell receptor 2B4
UniProt Synonym Protein Names
NK cell activation-inducing ligand; NAIL; NK cell type I receptor protein 2B4; NKR2B4; h2B4; SLAM family member 4; SLAMF4; Signaling lymphocytic activation molecule 4; CD_antigen: CD244
UniProt Gene Name
CD244
UniProt Synonym Gene Names
2B4; NAIL; NKR2B4; h2B4; SLAMF4
UniProt Entry Name
CD244_HUMAN
NCBI Protein Information
natural killer cell receptor 2B4; h2B4; SLAM family member 4; NK cell activation-inducing ligand; NK cell type I receptor protein 2B4; NK cell activation inducing ligand NAIL; signaling lymphocytic activation molecule 4

NCBI Summary for CD244

This gene encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]
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UniProt Comments for CD244

CD244: Modulate other receptor-ligand interactions to enhance leukocyte activation. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 1q23.3

Cellular Component: plasma membrane; integral to membrane; external side of plasma membrane

Molecular Function: protein binding; receptor activity

Biological Process: signal transduction; blood coagulation; leukocyte migration

Disease: Rheumatoid Arthritis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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