Human Cellexp CHIL3 Recombinant Protein – Cat# MBS849936

CHI3L3 (CHIL3) Human Cellexp Recombinant Protein

Name: CHIL3 Recombinant Protein; CHI3L3; Human Cellexp; MyBioSource
Brand: MyBioSource
SKU: MBS849936
Price: 390 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS849936

Chitinase 3-like 3 gene, also known as YM1 and ECF-L, encodes a precursor protein with 398 amino acid residues with a 21 residue signal sequence. Chitinase 3-like 3 protein is a lectin that binds saccharides with a free amino group, such as glucosamine or… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

CHI3L3 (Chil3), Recombinant Protein

Full Product Name

Human CellExp CHI3L3, Mouse Recombinant

Product Gene Name

Chil3 recombinant protein

Product Synonym Names

Chitinase-Like Protein 3; YM1/ECF-L; CHI3L3

Sequence

YQLMCYYTSW AKDRPIEGSF KPGNIDPCLC THLIYAFAGM QNNEITYTHE QDLRDYEALN GLKDKNTELK TLLAIGGWKF GPASFSAMVS TPQNRQIFIQ SVIRFLRQYN FDGLNLDWQY PGSRGSPPKD KHLFSVLVKE MRKAFEEESV EKDIPRLLLT STGAGIIDVI KSGYKIPELS QSLDYIQVMT YDLHDPKDGY TGENSPLYKS PYDIGKSADL NVDSIISYWK DHGAASEKLI VGFPAYGHTF ILSDPSKTGI GAPTISTGPP GKYTDESGLL AYYEVCTFLN EGATEVWDAP QEVPYAYQGN EWVGYDNVRS FKLKAQWLKD NNLGGAVVWP LDMDDFSGSF CHQRHFPLTS TLKGDLNIHS ASCKGPYVDH HHHHH

Host

HEK293 cells

Form/Format

Lyophilized from a 0.2 um filtered solution of PBS, pH7.4.

Purity/Purification

>=95% by SDS-PAGE

Preparation and Storage

Store at -20 degree C
Centrifuge the vial prior to opening.
Shelf life: ~12 months

Molecular Weight

44,458 Da

3D Structure

ModBase 3D Structure for O35744

Gene Source

Mouse

Reconstitution Instruction

Reconstitute in sterile deionized water to a concentration of 100 ug/ml.

Product Categories/Family for Chil3 recombinant protein

Proteins; Enzymes; Human cell expressed recombinant proteins; Proteins & Enzymes (A-Z)

Other Notes

Small volumes of Chil3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Chil3 purchase

MBS849936 is a recombinant protein targeting Chil3. Also known as Human CellExp CHI3L3, Mouse Recombinant. Host: HEK293 cells.

Additional Details

NCBI/Uniprot data below describe general gene information for Chil3. It may not necessarily be applicable to this product.

NCBI GI #

254281348

NCBI GeneID

12655

NCBI Accession #

NP_034022.2

UniProt Primary Accession #

O35744

UniProt Secondary Accession #

P70201; Q3U462; Q3UV87; Q61201

UniProt Related Accession #

O35744

GenBank Nucleotide #

NM_009892.3

NCBI Official Full Name

chitinase-like protein 3

NCBI Official Synonym Full Names

chitinase-like 3

NCBI Official Symbol

Chil3

NCBI Official Synonym Symbols

Ym1; ECF-L; Chi3l3; AI505981

UniProt Protein Name

Chitinase-like protein 3

UniProt Synonym Protein Names

Beta-N-acetylhexosaminidase Ym1; Chitinase-3-like protein 3; ECF-L; Eosinophil chemotactic cytokine; Secreted protein Ym1

Protein Family

Chitinase-like protein

UniProt Gene Name

Chil3

UniProt Synonym Gene Names

Chi3l3; Ym1

UniProt Entry Name

CHIL3_MOUSE

NCBI Protein Information

chitinase-like protein 3

NCBI Summary for Chil3

The protein encoded by this gene is similar to bacterial chitinases but lacks chitinase activity. The encoded protein is thought to function as a lectin and may be involved in inflammation and allergy. [provided by RefSeq, Sep 2015]

UniProt Comments for Chil3

CHI3L3: Lectin that binds saccharides with a free amino group, such as glucosamine or galactosamine. Binding to oligomeric saccharides is much stronger. Binds chitin and heparin. Has no chitinase activity. Has chemotactic activity for T-lymphocytes, bone marrow cells and eosinophils. May play a role in inflammation and allergy. Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

Protein type: EC 3.2.1.52

Cellular Component: cytoplasm; cytoplasmic membrane-bound vesicle; endoplasmic reticulum; extracellular region; nucleus

Molecular Function: beta-N-acetylhexosaminidase activity; carbohydrate binding; chitin binding; chitinase activity; hydrolase activity; hydrolase activity, acting on glycosyl bonds; hydrolase activity, hydrolyzing O-glycosyl compounds

Biological Process: carbohydrate metabolic process; chitin catabolic process; inflammatory response; metabolic process; polysaccharide catabolic process

Research Articles on Chil3

1. A significant increase of CHI3L3 mRNA expression was observed in the spinal cord of experimental autoimmune encephalitis mice compared to controls during the inflammatory phase.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Chil3 recombinant protein

Reference Product	PubMed Publications
Tnf recombinant protein	>1 publications with Chil3 and Tnf
Itgam recombinant protein	>1 publications with Chil3 and Itgam
Retnla recombinant protein	>1 publications with Chil3 and Retnla

Pathways associated with Chil3 recombinant protein

Products by Pathway	Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Carbohydrates Pathway antibodies	Metabolism Of Carbohydrates Pathway Diagram

Diseases associated with Chil3 recombinant protein

Disease Name	Pubmed Publications
Disease Models, Animal Antibodies	>3 publications with Chil3 and Disease Models, Animal
Inflammation Antibodies	>2 publications with Chil3 and Inflammation
Respiratory Tract Diseases Antibodies	>1 publications with Chil3 and Respiratory Tract Diseases
Respiratory Hypersensitivity Antibodies	>1 publications with Chil3 and Respiratory Hypersensitivity
Lung Diseases Antibodies	>1 publications with Chil3 and Lung Diseases
Necrosis Antibodies	>1 publications with Chil3 and Necrosis

Organs/Tissues associated with Chil3 recombinant protein

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>1 publications with Chil3 and Bone
Lung Antibodies	>1 publications with Chil3 and Lung
Blood Antibodies	>1 publications with Chil3 and Blood
Bone Marrow Antibodies	>1 publications with Chil3 and Bone Marrow