PLAT Recombinant Protein – Cat# MBS849946

TPA (PLAT) Recombinant Protein

Name: PLAT Recombinant Protein; TPA; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS849946
Price: 430 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS849946

Tissue plasminogen activator (PLAT or tPA) is a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Plasminogen is synthesized as a single chain which is cleaved by PLAT into the two chain disulfide linked… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

TPA (PLAT), Recombinant Protein

Full Product Name

TPA (311-562), Human Recombinant

Product Gene Name

PLAT recombinant protein

Product Synonym Gene Name

TPA

Product Synonym Names

Tissue-type plasminogen activator; EC 3.4.21.68; tPA; t-PA; t-plasminogen activator; TPA; T-PA; DKFZp686I03148; PLAT; TPA (311-562)

Sequence

ADPIKGGLFA DIASHPWQaa IFAKHRRSPG ERFLCGGILI SSCWILSAAH CFQERFPPHH LTVILGRTYR VVPGEEEQKF EVEKYIVHKE FDDDTYDNDI ALLQLKSDSS RCAQESSVVR TVCLPPADLQ LPDWTECELS GYGKHEALSP FYSERLKEAH VRLYPSSRCT SQHLLNRTVT DNMLCAGDTR SGGPQANLHD ACQGDSGGPL VCLNDGRMTL VGIISWGLGC GQKDVPGVYT KVTNYLDWIR DNMRPHHHHH H.

Host

Sf9, Baculovirus cells

Form/Format

Sterile Filtered colorless solution. TPA protein solution (0.5mg/ml) contains 50mM MES (pH5.0), 5mM CaCl2, 1mM DTT, 0.5M NaCl and 30% glycerol.

Purity/Purification

>= 95% by SDS-PAGE

Preparation and Storage

Store at 4 degree C if entire vial will be used within 2-4 weeks.
Store, frozen at store at -20 degree C for longer periods of time and for long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.Centrifuge the vial prior to opening. Shelf life: ~12 months

Molecular Weight

62,917 Da

Chromosome Location

Chromosome: 8; NC_000008.10 (42032236..42065194, complement). Location: 8p12

OMIM

173370

3D Structure

ModBase 3D Structure for P00750

Gene Source

Human

Product Categories/Family for PLAT recombinant protein

Proteins; Enzymes; Growth Factors

Other Notes

Small volumes of PLAT recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PLAT purchase

MBS849946 is a recombinant protein targeting PLAT. Also known as TPA (311-562), Human Recombinant. Host: Sf9, Baculovirus cells.

Additional Details

NCBI/Uniprot data below describe general gene information for PLAT. It may not necessarily be applicable to this product.

NCBI GI #

190032

NCBI GeneID

5327

NCBI Accession #

AAA60111.1

UniProt Primary Accession #

P00750

UniProt Secondary Accession #

Q15103; Q503B0; Q6PJA5; Q7Z7N2; Q86YK8; Q9BU99; Q9BZW1; A8K022; B2R8E8

UniProt Related Accession #

P00750

NCBI Official Full Name

tissue-type plasminogen activator

NCBI Official Synonym Full Names

plasminogen activator, tissue

NCBI Official Symbol

PLAT

NCBI Official Synonym Symbols

TPA; T-PA

UniProt Protein Name

Tissue-type plasminogen activator

Protein Family

Tissue-type plasminogen activator

UniProt Gene Name

PLAT

UniProt Synonym Gene Names

t-PA; t-plasminogen activator; tPA

UniProt Entry Name

TPA_HUMAN

NCBI Protein Information

tissue-type plasminogen activator; alteplase; reteplase; t-plasminogen activator; plasminogen activator, tissue type; tissue plasminogen activator (t-PA)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with PLAT recombinant protein

Products by Pathway	Pathway Diagram
Blood Clotting Cascade Pathway antibodies	Blood Clotting Cascade Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
Dissolution Of Fibrin Clot Pathway antibodies	Dissolution Of Fibrin Clot Pathway Diagram
Endochondral Ossification Pathway antibodies	Endochondral Ossification Pathway Diagram
Hemostasis Pathway antibodies	Hemostasis Pathway Diagram
Selenium Pathway antibodies	Selenium Pathway Diagram
Senescence And Autophagy Pathway antibodies	Senescence And Autophagy Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram

Diseases associated with PLAT recombinant protein

Disease Name	Pubmed Publications
Inflammation Antibodies	>27 publications with PLAT and Inflammation
Arterial Occlusive Diseases Antibodies	>22 publications with PLAT and Arterial Occlusive Diseases
Atherosclerosis Antibodies	>20 publications with PLAT and Atherosclerosis
Thrombosis Antibodies	>19 publications with PLAT and Thrombosis
Cerebral Infarction Antibodies	>14 publications with PLAT and Cerebral Infarction
Necrosis Antibodies	>14 publications with PLAT and Necrosis
Stroke Antibodies	>13 publications with PLAT and Stroke
Myocardial Infarction Antibodies	>12 publications with PLAT and Myocardial Infarction
Kidney Diseases Antibodies	>9 publications with PLAT and Kidney Diseases
Embolism and Thrombosis Antibodies	>9 publications with PLAT and Embolism and Thrombosis

Organs/Tissues associated with PLAT recombinant protein

Organ/Tissue Name	Pubmed Publications
Vascular Antibodies	>47 publications with PLAT and Vascular
Liver Antibodies	>44 publications with PLAT and Liver
Brain Antibodies	>37 publications with PLAT and Brain
Heart Antibodies	>36 publications with PLAT and Heart
Lung Antibodies	>29 publications with PLAT and Lung
Muscle Antibodies	>26 publications with PLAT and Muscle
Intestine Antibodies	>17 publications with PLAT and Intestine
Bone Antibodies	>17 publications with PLAT and Bone
Embryonic Tissue Antibodies	>16 publications with PLAT and Embryonic Tissue
Kidney Antibodies	>14 publications with PLAT and Kidney