NT-proBNP Antibody – Mouse Monoclonal

Natriuretic peptides are hormones that are produced by the cardiac tissues and are involved in functions such as maintaining homeostasis of body fluids and regulating blood pressure. There are three major known natriuretic peptides: Atrial natriuretic peptide (ANP), B-type natriuretic peptide (BNP) and C-type NP. BNP is first synthesized as pre-proBNP in the myocardium of the ventricle, which is then cleaved first to proBNP, then to active BNP (34 amino acids) and an inactive N-terminal proBNP (NT-proBNP). Although BNP and NT-proBNP are secreted in equal concentrations, NT-proBNP has a half-life of 120 mins. Increased levels of NT-proBNP are found with increased age, hypertrophy of the ventricles, fibrillation the atria and heart failure. Therefore NT-proBNP serves as an important test marker for cardiac failure.

Small volumes of anti-NT-proBNP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS849955 is an antibody targeting NT-proBNP. Also known as Anti-NT-proBNP (64-67) Capture Antibody. Reactive in NT-proBNP. Host: Mouse.