Human Cellexp SIGLEC15 Recombinant Protein – Cat# MBS849967

Siglec-15 (SIGLEC15) Human Cellexp Recombinant Protein

Name: SIGLEC15 Recombinant Protein; Siglec-15; Human Cellexp; MyBioSource
Brand: MyBioSource
SKU: MBS849967
Price: 240 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS849967

Siglec-15 is a transmembrane glycoprotein of the siglecs family that participates in the immune regulatory systems through the recognition of their glycan ligands. Siglecs, short for sialic acid-binding immunoglobulin (Ig) -like lectins, are primarily… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

Siglec-15 (SIGLEC15), Recombinant Protein

Full Product Name

Human CellExp Siglec-15, Human Recombinant

Product Gene Name

SIGLEC15 recombinant protein

Product Synonym Names

Sialic acid-binding immunoglobulin (Ig)-like lectin 15; CD33 antigen-like 3; CD33 molecule-like 3; CD33L3

Host

HEK293 cells

Form/Format

Lyophilized from 0.22 um filtered PBS (pH7.4) with 5% trehalose

Purity/Purification

>=95% by SDS-PAGE

Preparation and Storage

Store at -20 degree C
Centrifuge the vial prior to opening.
Shelf life: ~12 months

Molecular Weight

18,086 Da

3D Structure

ModBase 3D Structure for Q6ZMC9

Gene Source

Human

Reconstitution Instruction

Reconstitute in sterile PBS, pH 7.4 up to 0.2ug/ul.

Product Categories/Family for SIGLEC15 recombinant protein

Cytokines; Growth Factors & Hormones; CDs; Cytokines; Cytokines & Growth Factors (A-Z)

Other Notes

Small volumes of SIGLEC15 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SIGLEC15 purchase

MBS849967 is a recombinant protein targeting SIGLEC15. Also known as Human CellExp Siglec-15, Human Recombinant. Host: HEK293 cells.

Additional Details

NCBI/Uniprot data below describe general gene information for SIGLEC15. It may not necessarily be applicable to this product.

NCBI GI #

47106069

NCBI GeneID

284266

NCBI Accession #

NP_998767

UniProt Primary Accession #

Q6ZMC9

UniProt Secondary Accession #

A8K2Y5; B4DVQ9

UniProt Related Accession #

Q6ZMC9

GenBank Nucleotide #

NM_213602.2

NCBI Official Full Name

sialic acid-binding Ig-like lectin 15

NCBI Official Synonym Full Names

sialic acid binding Ig-like lectin 15

NCBI Official Symbol

SIGLEC15

NCBI Official Synonym Symbols

CD33L3; HsT1361; SIGLEC-15

UniProt Protein Name

Sialic acid-binding Ig-like lectin 15

UniProt Synonym Protein Names

CD33 antigen-like 3

Protein Family

Sialic acid-binding Ig-like lectin

UniProt Gene Name

SIGLEC15

UniProt Synonym Gene Names

CD33L3; Siglec-15

UniProt Entry Name

SIG15_HUMAN

NCBI Protein Information

sialic acid-binding Ig-like lectin 15; CD33 antigen-like 3; CD33 molecule-like 3

UniProt Comments for SIGLEC15

CD33L3: Binds sialylated glycoproteins. Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 18q12.3

Cellular Component: protein complex; integral to membrane; plasma membrane

Biological Process: regulation of bone resorption; regulation of actin cytoskeleton organization and biogenesis; innate immune response

Research Articles on SIGLEC15

1. Siglec-15 recognizes the tumoral sTn antigen and transduces a signal for enhanced TGF-beta secretion in TAMs

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with SIGLEC15 recombinant protein

Reference Product	PubMed Publications
TYROBP recombinant protein	>1 publications with SIGLEC15 and TYROBP

Pathways associated with SIGLEC15 recombinant protein

Products by Pathway	Pathway Diagram
DAP12 Interactions Pathway antibodies	DAP12 Interactions Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram

Organs/Tissues associated with SIGLEC15 recombinant protein

Organ/Tissue Name	Pubmed Publications
Spleen Antibodies	>1 publications with SIGLEC15 and Spleen
Blood Antibodies	>1 publications with SIGLEC15 and Blood