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TDGF1 Antibody – Mouse

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS850065

This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth.… More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TDGF1, Antibody
Full Product Name
TDGF1 Antibody
Product Gene Name
Product Synonym Names
CR; CRGF; CRIPTO; TDGF1
Isotype
IgG1
Clone Number
3A6
Host
Mouse
Species Reactivity
Human
Form/Format
Ascitic fluid containing 0.03% sodium azide.
Preparation and Storage
Store at 4 degree C, for long term storage, store at-20 degree C.
Molecular Weight
21kDa
OMIM
187395
3D Structure
ModBase 3D Structure for P13385
Immunogen
Purified recombinant fragment of human TDGF1 expressed in E. Coli.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-TDGF1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-TDGF1 antibody
WB: 1:500-1:2000
ELISA: 1:10000

Western Blot (WB) of anti-TDGF1 antibody

Figure 1: Western blot analysis using TDGF1 mAb against HEK293 (1) and TDGF1-hIgGFc transfected HEK293 (2) cell lysate.
Mouse Anti-TDGF1 Antibody – Cat# MBS850065

Testing Data of anti-TDGF1 antibody

Mouse Anti-TDGF1 Antibody, Testing Data – Cat# MBS850065

Other Notes

Small volumes of anti-TDGF1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TDGF1 purchase

MBS850065 is an antibody targeting TDGF1. Also known as TDGF1 Antibody. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for TDGF1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
teratocarcinoma-derived growth factor 1 isoform 2
NCBI Official Synonym Full Names
teratocarcinoma-derived growth factor 1
NCBI Official Symbol
TDGF1
NCBI Official Synonym Symbols
CR; CRGF; CRIPTO
UniProt Protein Name
Teratocarcinoma-derived growth factor 1
UniProt Synonym Protein Names
Cripto-1 growth factor; CRGF; Epidermal growth factor-like cripto protein CR1
UniProt Gene Name
TDGF1
UniProt Synonym Gene Names
CRIPTO; CRGF
NCBI Protein Information
teratocarcinoma-derived growth factor 1

NCBI Summary for TDGF1

This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects. Pseudogenes of this gene are found on chromosomes 2, 3, 6, 8, 19 and X. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
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UniProt Comments for TDGF1

GPI-anchored cell membrane protein involved in Nodal signaling. Cell-associated TDGF1 acts as a Nodal coreceptor in cis. Shedding of TDGF1 by TMEM8A modulates Nodal signaling by allowing soluble TDGF1 to act as a Nodal coreceptor on other cells (PubMed:27881714). Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm (PubMed:11909953).
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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