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TBL1Y Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS850187

The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TBL1Y, Antibody
Full Product Name
TBL1Y Antibody
Product Gene Name
Product Synonym Names
Mouse monoclonal IgG to TBL1Y
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
Protein G-Sepharose affinity purified.
Preparation and Storage
Aliquot and store at-20 degree C. Avoid repeated freeze/thaw cycles.
Molecular Weight
56,688 Da
OMIM
400033
Immunogen
Recombinant full length of Human TBL1Y
Preservative
0.02% Sodium Azide and 50% glycerol, 1% BSA, PBS, pH7.4.
Cellular Localization
Nucleus
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-TBL1Y antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-TBL1Y antibody
ELISA: 1:5000-1:20000
WB: 1:100-1:2000

Testing Data of anti-TBL1Y antibody

TBL1 antibody at 1/500dilution. Nuclear extract of Hela cell 40ug/Lane. Predicted band size: 58Kda. Observed band size: 60Kda.
Anti-TBL1Y Antibody – Cat# MBS850187

Other Notes

Small volumes of anti-TBL1Y antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TBL1Y purchase

MBS850187 is an antibody targeting TBL1Y. Also known as TBL1Y Antibody. Reactive in Human.

Additional Details

NCBI/Uniprot data below describe general gene information for TBL1Y. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
transducin beta-like 1
NCBI Official Synonym Full Names
transducin beta like 1 Y-linked
NCBI Official Symbol
TBL1Y
NCBI Official Synonym Symbols
TBL1
UniProt Protein Name
F-box-like/WD repeat-containing protein TBL1Y
UniProt Synonym Protein Names
Transducin beta-like protein 1Y; Transducin-beta-like protein 1, Y-linked
UniProt Gene Name
TBL1Y
UniProt Synonym Gene Names
TBL1
NCBI Protein Information
F-box-like/WD repeat-containing protein TBL1Y

NCBI Summary for TBL1Y

The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This gene is highly similar to TBL1X gene in nucleotide sequence and protein sequence, but the TBL1X gene is located on chromosome X and this gene is on chromosome Y. This gene has three alternatively spliced transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
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UniProt Comments for TBL1Y

F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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