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E7 Antibody – Mouse

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS850314

MBS850314 is an antibody targeting E7. Also known as E7 Antibody. Reactive in Human. Host: Mouse. E7 transforming protein (Human papillomavirus type 16). More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
E7, Antibody
Full Product Name
E7 Antibody
Product Gene Name
anti-E7 antibody
Product Synonym Names
E7; HpV16gp2
Isotype
IgG1
Host
Mouse
Species Reactivity
Human
Form/Format
Ascitic fluid containing 0.03% sodium azide.
Preparation and Storage
Store at 4 degree C, for long term storage, store at-20 degree C.
Molecular Weight
21kDa
3D Structure
ModBase 3D Structure for P03129
Immunogen
Purified recombinant fragment of E7 expressed in E. Coli.

Product Categories/Family for anti-E7 antibody

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-E7 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-E7 antibody
WB: 1:500-1:2000
IHC: 1:200-1:1000
ELISA: 1:10000

Western Blot (WB) of anti-E7 antibody

Figure 1: Western blot analysis using E7 mAb against recombinant protein.
Mouse Anti-E7 Antibody – Cat# MBS850314

Immunohistochemistry (IHC) of anti-E7 antibody

Figure 2: Immunohistochemical analysis of paraffin-embedded placenta tissues (left) and ovarian cancer (right) using E7 mouse mAb with DAB staining.
Mouse Anti-E7 Antibody, Immunohistochemistry (IHC) – Cat# MBS850314

Testing Data of anti-E7 antibody

Mouse Anti-E7 Antibody, Testing Data – Cat# MBS850314

Other Notes

Small volumes of anti-E7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for E7. It may not necessarily be applicable to this product.

NCBI GI #
9627105
NCBI GeneID
1489079
NCBI Accession #
NP_041326.1
UniProt Primary Accession #
P03129
UniProt Related Accession #
P03129
GenBank Nucleotide #
NC_001526.4
NCBI Official Full Name
transforming protein E7
NCBI Official Symbol
E7
UniProt Protein Name
Protein E7
UniProt Gene Name
E7
NCBI Protein Information
transforming protein E7

UniProt Comments for E7

Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. E7 protein has both transforming and trans-activating activities. Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation. Plays also a role in the inhibition of both antiviral and antiproliferative functions of host interferon alpha. Interaction with host TMEM173/STING impairs the ability of TMEM173/STING to sense cytosolic DNA and promote the production of type I interferon (IFN-alpha and IFN-beta).
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Research Articles on E7

1. direct evidence that both A3A and HPV16 E7 interact with CUL2, suggesting that the E7-CUL2 complex formed during HPV infection may regulate A3A protein levels in the cell.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-E7 antibody

 Reference Product  PubMed Publications
 DNAJA3 antibody  >2 publications with E7 and DNAJA3
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