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TBL1XR1 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS850368

TBLR1 is an F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. It plays an essential role in transcription activation mediated by nuclear receptors and probably acts as an… More details

$295 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TBL1XR1, Antibody
Full Product Name
TBL1XR1 Antibody
Product Gene Name
Product Synonym Names
Mouse monoclonal to TBL1XR1
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
Protein G-Sepharose affinity purified.
Preparation and Storage
Aliquot and store at-20 degree C. Avoid repeated freeze/thaw cycles.
Molecular Weight
55,595 Da
OMIM
602342
Immunogen
Recombinant full length of Human TBLR1.
Preservative
0.02% Sodium Azide and 50% glycerol, 1% BSA, PBS, pH7.4.
Cellular Localization
Nucleus
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-TBL1XR1 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-TBL1XR1 antibody
ELISA: 1:5000-1:20000
WB: 1:100-1:2000

Testing Data of anti-TBL1XR1 antibody

TBL1XR1 antibody at 1/1000 dilution. K562 Whole cell lysate 40ug/lane. Predicted band size: 60KDa. Observed band size: 60KDa.
Anti-TBL1XR1 Antibody – Cat# MBS850368

Other Notes

Small volumes of anti-TBL1XR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TBL1XR1 purchase

MBS850368 is an antibody targeting TBL1XR1. Also known as TBL1XR1 Antibody. Reactive in Human.

Additional Details

NCBI/Uniprot data below describe general gene information for TBL1XR1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Homo sapiens nuclear receptor co-repressor/HDAC3 complex subunit TBLR1 (TBLR1) mRNA, complete cds
NCBI Official Synonym Full Names
transducin beta like 1 X-linked receptor 1
NCBI Official Symbol
TBL1XR1
NCBI Official Synonym Symbols
C21; DC42; IRA1; MRD41; TBLR1
UniProt Protein Name
F-box-like/WD repeat-containing protein TBL1XR1
UniProt Synonym Protein Names
Nuclear receptor corepressor/HDAC3 complex subunit TBLR1; TBL1-related protein 1; Transducin beta-like 1X-related protein 1
UniProt Gene Name
TBL1XR1
UniProt Synonym Gene Names
IRA1; TBLR1
NCBI Protein Information
F-box-like/WD repeat-containing protein TBL1XR1

NCBI Summary for TBL1XR1

This gene is a member of the WD40 repeat-containing gene family and shares sequence similarity with transducin (beta)-like 1X-linked (TBL1X). The protein encoded by this gene is thought to be a component of both nuclear receptor corepressor (N-CoR) and histone deacetylase 3 (HDAC 3) complexes, and is required for transcriptional activation by a variety of transcription factors. Mutations in these gene have been associated with some autism spectrum disorders, and one finding suggests that haploinsufficiency of this gene may be a cause of intellectual disability with dysmorphism. Mutations in this gene as well as recurrent translocations involving this gene have also been observed in some tumors. [provided by RefSeq, Mar 2016]
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UniProt Comments for TBL1XR1

F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of N-Cor complex, thereby allowing cofactor exchange, and transcription activation.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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