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KDM6A Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS850395

KDM6A is an 154 kDa ubiquitously transcribed X chromosome tetraticopeptide repeat protein that is predicted to interact with TLE1. KDM6A contains a jumonji C domain and specifically demethylates di and tri methyl histone H3 at K27. More details

$295 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
KDM6A, Antibody
Full Product Name
KDM6A Antibody
Product Gene Name
Product Synonym Names
Mouse monoclonal IgG to KDM6A
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
Protein G-Sepharose affinity purified
Preparation and Storage
Aliquot and store at-20 degree C. Avoid repeated freeze/thaw cycles.
Molecular Weight
154,177 Da
OMIM
300128
3D Structure
ModBase 3D Structure for O15550
Immunogen
Recombinant fragment of Human KDM6A (N-terminus).
Preservative
0.02% Sodium Azide, 50% glycerol, 1% BSA, PBS, pH7.4.
Cellular Localization
Nucleus
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-KDM6A antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-KDM6A antibody
ELISA: 1:5000-1:20000
WB: 1:100-1:2000

Testing Data of anti-KDM6A antibody

KDM6A antibody at 1/2000 dilution interacts with recombinant KDM6A protein with a GST tag. Predicted band size: 40Kda. Observed band size: 40Kda.
Anti-KDM6A Antibody – Cat# MBS850395

Other Notes

Small volumes of anti-KDM6A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KDM6A purchase

MBS850395 is an antibody targeting KDM6A. Also known as KDM6A Antibody. Reactive in Human.

Additional Details

NCBI/Uniprot data below describe general gene information for KDM6A. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
lysine-specific demethylase 6A isoform 3
NCBI Official Synonym Full Names
lysine demethylase 6A
NCBI Official Symbol
KDM6A
NCBI Official Synonym Symbols
UTX; KABUK2; bA386N14.2
UniProt Protein Name
Lysine-specific demethylase 6A
UniProt Synonym Protein Names
Histone demethylase UTX; Ubiquitously-transcribed TPR protein on the X chromosome; Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein
UniProt Gene Name
KDM6A
UniProt Synonym Gene Names
UTX
NCBI Protein Information
lysine-specific demethylase 6A

NCBI Summary for KDM6A

This gene is located on the X chromosome and is the corresponding locus to a Y-linked gene which encodes a tetratricopeptide repeat (TPR) protein. The encoded protein of this gene contains a JmjC-domain and catalyzes the demethylation of tri/dimethylated histone H3. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2014]
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UniProt Comments for KDM6A

Histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code (PubMed:17851529, PubMed:17713478, PubMed:17761849). Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27' (PubMed:17851529, PubMed:17713478, PubMed:17761849). Plays a central role in regulation of posterior development, by regulating HOX gene expression (PubMed:17851529). Demethylation of 'Lys-27' of histone H3 is concomitant with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A (PubMed:17761849). Plays a demethylase-independent role in chromatin remodeling to regulate T-box family member-dependent gene expression ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-KDM6A antibody

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