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TUG Antibody – Mouse

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS850456

The TUG protein contains a UBX domain, for GLUT4. In truncated form, TUG acts in a dominant-negative manner to inhibit insulin-stimulated GLUT4 redistribution in Chinese hamster ovary cells and 3T3-L1 adipocytes. Full-length TUG forms a complex specifically… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TUG, Antibody
Full Product Name
Mouse TUG Antibody
Product Gene Name
Product Synonym Names
ASPCR1; ASPL; ASPS; RCC17; TUG; UBXD9; UBXN9
Isotype
IgG1
Clone Number
4A11A6G11
Host
Mouse
Species Reactivity
Mouse
Form/Format
Purified antibody in PBS containing 0.03% sodium azide.
Preparation and Storage
Store at 4 degree C, for long term storage, store at-20 degree C
Molecular Weight
37,910 Da
OMIM
606236
3D Structure
ModBase 3D Structure for Q9BZE9
Immunogen
Purified recombinant fragment of TUG expressed in E. Coli.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-TUG antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-TUG antibody
WB: 1:500-1:2000
ELISA: 1:10000

Western Blot (WB) of anti-TUG antibody

Figure 1. Western blot analysis using TUG mouse mAb against NIH/3T3 cell lysate.
Mouse Anti-TUG Antibody – Cat# MBS850456

Other Notes

Small volumes of anti-TUG antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TUG purchase

MBS850456 is an antibody targeting TUG. Also known as Mouse TUG Antibody. Reactive in Mouse. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for TUG. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
tether containing UBX domain for GLUT4 isoform 2
NCBI Official Synonym Full Names
ASPSCR1, UBX domain containing tether for SLC2A4
NCBI Official Symbol
ASPSCR1
NCBI Official Synonym Symbols
TUG; ASPL; ASPS; RCC17; UBXD9; UBXN9; ASPCR1
UniProt Protein Name
Tether containing UBX domain for GLUT4
UniProt Synonym Protein Names
Alveolar soft part sarcoma chromosomal region candidate gene 1 protein; Alveolar soft part sarcoma locus; Renal papillary cell carcinoma protein 17; UBX domain-containing protein 9
UniProt Gene Name
ASPSCR1
UniProt Synonym Gene Names
ASPL; RCC17; TUG; UBXD9; UBXN9
NCBI Protein Information
tether containing UBX domain for GLUT4

NCBI Summary for TUG

The protein encoded by this gene contains a UBX domain and interacts with glucose transporter type 4 (GLUT4). This protein is a tether, which sequesters the GLUT4 in intracellular vesicles in muscle and fat cells in the absence of insulin, and redistributes the GLUT4 to the plasma membrane within minutes of insulin stimulation. Translocation t(X;17)(p11;q25) of this gene with transcription factor TFE3 gene results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas. Multiple alternatively spliced transcript variants have been found. [provided by RefSeq, Oct 2011]
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UniProt Comments for TUG

Tethering protein that sequesters GLUT4-containing vesicles in the cytoplasm in the absence of insulin. Modulates the amount of GLUT4 that is available at the cell surface (). Enhances VCP methylation catalyzed by VCPKMT.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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