CYFRA21-1 Antibody

IgG2a

3D4

Ascites

In 10mM Sodium Phosphate, 0.15M SodiumChloride, pH 7.4

>90% pure (SDS-PAGE).
Protein A chromatography.

Ks 19.1 represents an excellent marker to discriminate glandular epithelial carcinomafrom those of different origin. No reaction with hepatocellular carcinoma.Polypeptide reacting: Mr 40 000 polypeptide (keratin K19; formerly also designatedcytokeratin 19) of human glandular epithelia. The epitope has been localized on aa.311-335 (QSQLSMKAALEDTLAETEARFGAQLA) of the alpha-helical fragment.Tumors specifically detected: All tested adenocarcinoma; cholangio ca. of liver; renal cell carcinoma; transitional cell ca. of the bladder; ovary ca.; squamous cell ca. of cervix, bronchus and lung (intermediate type); mesothelioma; carcinoid tumor of bronchus; breast ca.; thymoma.

Store at-20 degree C. Avoid multiple freeze/thaw cycles.

Keratin K19 of Mr 40 000; from cultured human MCF-7 cells

Manufactured in an ISO 9001:2015 Certified Laboratory.