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PSIP1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS850615

Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal… More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PSIP1, Monoclonal Antibody
Full Product Name
PSIP1 Mouse Monoclonal Antibody
Product Gene Name
anti-PSIP1 antibody
Product Synonym Names
p52; p75; PAIP; DFS70; LEDGF; PSIP2; MGC74712; PSIP1
Clonality
Monoclonal
Isotype
IgG1
Clone Number
6E4
Host
Mouse
Species Reactivity
Human, Monkey, Rat
Form/Format
Ascitic fluid containing 0.03% sodium azide.
Preparation and Storage
Store at 4 degree C, for long term storage, store at-20 degree C.
Molecular Weight
75kDa
OMIM
603620
3D Structure
ModBase 3D Structure for O75475
Immunogen
Purified recombinant fragment 214-332aa of human CARM1 expressed in E. Coli.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-PSIP1 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-PSIP1 antibody
WB: 1:500-1:2000
IHC: 1:200-1:1000
IF: 1:200-1:1000
ELISA: 1:10000

Western Blot (WB) of anti-PSIP1 antibody

Figure 1: Western blot analysis using PSIP1 mouse mAb against HepG2 (1), Jurkat (2), K562 (3), Cos7 (4), PC-12 (5), Hela (6), and NIH/3T3 (7) cell lysate.
Mouse Anti-PSIP1 Monoclonal Antibody – Cat# MBS850615

Immunohistochemistry (IHC) of anti-PSIP1 antibody

Figure 2: Immunohistochemical analysis of paraffin-embedded breast cancer tissues (left) and ovarian cancer tissues (right) using PSIP1 mouse mAb with DAB staining.
Mouse Anti-PSIP1 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS850615

Testing Data of anti-PSIP1 antibody

Mouse Anti-PSIP1 Monoclonal Antibody, Testing Data – Cat# MBS850615

Other Notes

Small volumes of anti-PSIP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PSIP1 purchase

MBS850615 is an antibody targeting PSIP1. Also known as PSIP1 Mouse Monoclonal Antibody. Reactive in Human, Monkey, Rat. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for PSIP1. It may not necessarily be applicable to this product.

NCBI GI #
190014588
NCBI GeneID
11168
NCBI Accession #
NP_001121689.1
UniProt Primary Accession #
O75475
UniProt Secondary Accession #
O00256; O95368; Q6P391; Q86YB9; Q9NZI3; Q9UER6; D3DRI9
UniProt Related Accession #
O75475
GenBank Nucleotide #
NM_001128217.2
NCBI Official Full Name
PC4 and SFRS1-interacting protein isoform 2
NCBI Official Synonym Full Names
PC4 and SFRS1 interacting protein 1
NCBI Official Symbol
PSIP1
NCBI Official Synonym Symbols
p52; p75; PAIP; DFS70; LEDGF; PSIP2
UniProt Protein Name
PC4 and SFRS1-interacting protein
UniProt Synonym Protein Names
CLL-associated antigen KW-7; Dense fine speckles 70 kDa protein; DFS 70; Lens epithelium-derived growth factor; Transcriptional coactivator p75/p52
Protein Family
Lens epithelium-derived growth factor
UniProt Gene Name
PSIP1
UniProt Synonym Gene Names
DFS70; LEDGF; PSIP2; DFS 70
NCBI Protein Information
PC4 and SFRS1-interacting protein

UniProt Comments for PSIP1

Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration.
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Research Articles on PSIP1

1. findings suggest a novel role of LEDGF/p75 in protecting the unintegrated 3' processed linear HIV-1 cDNA from exonucleolytic degradation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PSIP1 antibody

 Reference Product  PubMed Publications
 MEN1 antibody  >5 publications with PSIP1 and MEN1
 MLL antibody  >4 publications with PSIP1 and MLL
 SP1 antibody  >3 publications with PSIP1 and SP1
 RBBP8 antibody  >2 publications with PSIP1 and RBBP8
 PABPC1 antibody  >1 publications with PSIP1 and PABPC1
 HSPA2 antibody  >1 publications with PSIP1 and HSPA2
 SRSF1 antibody  >1 publications with PSIP1 and SRSF1

Pathways associated with anti-PSIP1 antibody

 Products by Pathway  Pathway Diagram
 2-LTR Circle Formation Pathway antibodies  2-LTR Circle Formation Pathway Diagram
 APOBEC3G Mediated Resistance To HIV-1 Infection Pathway antibodies  APOBEC3G Mediated Resistance To HIV-1 Infection Pathway Diagram
 Autointegration Results In Viral DNA Circles Pathway antibodies  Autointegration Results In Viral DNA Circles Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Early Phase Of HIV Life Cycle Pathway antibodies  Early Phase Of HIV Life Cycle Pathway Diagram
 HIV Infection Pathway antibodies  HIV Infection Pathway Diagram
 HIV Life Cycle Pathway antibodies  HIV Life Cycle Pathway Diagram
 Host Interactions Of HIV Factors Pathway antibodies  Host Interactions Of HIV Factors Pathway Diagram
 Infectious Disease Pathway antibodies  Infectious Disease Pathway Diagram
 Integration Of Provirus Pathway antibodies  Integration Of Provirus Pathway Diagram

Diseases associated with anti-PSIP1 antibody

 Disease Name  Pubmed Publications
 Leukemia, Myeloid, Acute Antibodies  >5 publications with PSIP1 and Leukemia, Myeloid, Acute
 Cell Transformation, Neoplastic Antibodies  >4 publications with PSIP1 and Cell Transformation, Neoplastic
 Brain Diseases Antibodies  >4 publications with PSIP1 and Brain Diseases
 Necrosis Antibodies  >4 publications with PSIP1 and Necrosis
 Nervous System Diseases Antibodies  >4 publications with PSIP1 and Nervous System Diseases
 Adenocarcinoma Antibodies  >3 publications with PSIP1 and Adenocarcinoma
 Anemia Antibodies  >3 publications with PSIP1 and Anemia
 Lung Diseases Antibodies  >2 publications with PSIP1 and Lung Diseases
 Breast Neoplasms Antibodies  >2 publications with PSIP1 and Breast Neoplasms
 Hepatomegaly Antibodies  >1 publications with PSIP1 and Hepatomegaly

Organs/Tissues associated with anti-PSIP1 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >35 publications with PSIP1 and Blood
 Nerve Antibodies  >11 publications with PSIP1 and Nerve
 Connective Tissue Antibodies  >9 publications with PSIP1 and Connective Tissue
 Eye Antibodies  >8 publications with PSIP1 and Eye
 Brain Antibodies  >6 publications with PSIP1 and Brain
 Bone Antibodies  >5 publications with PSIP1 and Bone
 Prostate Antibodies  >5 publications with PSIP1 and Prostate
 Skin Antibodies  >4 publications with PSIP1 and Skin
 Bone Marrow Antibodies  >3 publications with PSIP1 and Bone Marrow
 Ganglia Antibodies  >3 publications with PSIP1 and Ganglia
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