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NKX3A Antibody – Mouse

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS850643

Nkx3.1 is a transcription factor that may play an important role in regulating proliferation of glandular epithelium and in the formation of ducts in the prostate. It has been thought to be one of the target genes of the 8p21 loss of heterozygosity, common in… More details

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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
NKX3A, Antibody
Full Product Name
NKX3A Antibody
Product Gene Name
Product Synonym Names
NKX3; BAPX2; NKX3A; NKX3.1; NKX3-1
Isotype
IgG1
Clone Number
4H4
Host
Mouse
Species Reactivity
Human
Form/Format
Ascitic fluid containing 0.03% sodium azide.
Preparation and Storage
Store at 4 degree C, for long term storage, store at-20 degree C.
Molecular Weight
26.3kDa
OMIM
602041
3D Structure
ModBase 3D Structure for Q99801
Immunogen
Purified recombinant fragment of human NKX3A expressed in E. Coli.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-NKX3A antibody
Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS), ELISA (EIA)
Application Notes for anti-NKX3A antibody
WB: 1:500-1:2000
IHC: 1:200-1:1000
FC: 1:200-1:400
ELISA: 1:10000

Western Blot (WB) of anti-NKX3A antibody

Figure 1: Western blot analysis using NKX3A mouse mAb against LNCaP (1) cell lysate.
Mouse Anti-NKX3A Antibody – Cat# MBS850643

Immunohistochemistry (IHC) of anti-NKX3A antibody

Figure 2: Immunohistochemical analysis of paraffin-embedded human prostata tissues (A, B) using anti-NKX3A antibody with DAB staining.
Mouse Anti-NKX3A Antibody, Immunohistochemistry (IHC) – Cat# MBS850643

Immunohistochemistry (IHC) of anti-NKX3A antibody

Figure 3: Immunohistochemical analysis of paraffin-embedded human Liver tissues using NKX3A mAb
Mouse Anti-NKX3A Antibody, Immunohistochemistry (IHC) – Cat# MBS850643

Other Notes

Small volumes of anti-NKX3A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NKX3A purchase

MBS850643 is an antibody targeting NKX3A. Also known as NKX3A Antibody. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for NKX3A. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
homeobox protein Nkx-3.1 isoform 2
NCBI Official Synonym Full Names
NK3 homeobox 1
NCBI Official Symbol
NKX3-1
NCBI Official Synonym Symbols
NKX3; BAPX2; NKX3A; NKX3.1
UniProt Protein Name
Homeobox protein Nkx-3.1
UniProt Synonym Protein Names
Homeobox protein NK-3 homolog A
UniProt Gene Name
NKX3-1
UniProt Synonym Gene Names
NKX3.1; NKX3A
NCBI Protein Information
homeobox protein Nkx-3.1

NCBI Summary for NKX3A

This gene encodes a homeobox-containing transcription factor. This transcription factor functions as a negative regulator of epithelial cell growth in prostate tissue. Aberrant expression of this gene is associated with prostate tumor progression. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jan 2012]
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UniProt Comments for NKX3A

Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-NKX3A antibody

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