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ATP2C1 Antibody – Mouse

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS850671

ATP2C1, also known as PMR1, it belongs to the family of P-type cation transport ATPases. This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of the calcium. The human homologue, ATP2C1 (also designated SPLA in rat), also… More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
ATP2C1, Antibody
Full Product Name
ATP2C1 Antibody
Product Gene Name
anti-ATP2C1 antibody
Product Synonym Names
HHD; BCPM; PMR1; SPCA1
Isotype
IgG1
Clone Number
4G12
Host
Mouse
Species Reactivity
Human, Monkey
Form/Format
Ascitic fluid containing 0.03% sodium azide.
Preparation and Storage
Store at 4 degree C, for long term storage, store at-20 degree C.
Molecular Weight
100kDa
OMIM
169600
3D Structure
ModBase 3D Structure for P98194
Immunogen
Purified recombinant fragment of ATP2C1 expressed in E. Coli.

Product Categories/Family for anti-ATP2C1 antibody

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-ATP2C1 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-ATP2C1 antibody
WB: 1:500-1:2000
IHC: 1:200-1:1000
ELISA: 1:10000

Western Blot (WB) of anti-ATP2C1 antibody

Figure 1: Western blot analysis using ATP2C1 mouse mAb against human recombinant ATP2C1.
Mouse Anti-ATP2C1 Antibody – Cat# MBS850671

Western Blot (WB) of anti-ATP2C1 antibody

Figure 2: Western blot analysis using ATP2C1 mouse mAb against A431 (1), Hela (2) and HEK293 (3) cell lysate.
Mouse Anti-ATP2C1 Antibody, Western Blot (WB) – Cat# MBS850671

Immunohistochemistry (IHC) of anti-ATP2C1 antibody

Figure 3: Immunohistochemical analysis of paraffin-embedded human ovarian cancer (left) and breast cancer (right) tissues using ATP2C1 mouse mAb with DAB staining.
Mouse Anti-ATP2C1 Antibody, Immunohistochemistry (IHC) – Cat# MBS850671

Other Notes

Small volumes of anti-ATP2C1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ATP2C1 purchase

MBS850671 is an antibody targeting ATP2C1. Also known as ATP2C1 Antibody. Reactive in Human, Monkey. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for ATP2C1. It may not necessarily be applicable to this product.

NCBI GI #
48762687
NCBI GeneID
27032
NCBI Accession #
NP_001001485.1
UniProt Primary Accession #
P98194
UniProt Secondary Accession #
O76005; Q86V72; Q86V73; Q8N6V1; Q8NCJ7; B2RAT7; B4DSW3; B7Z3X9; G3XAH8; G8JLN9
UniProt Related Accession #
P98194
GenBank Nucleotide #
NM_001001485.2
NCBI Official Full Name
calcium-transporting ATPase type 2C member 1 isoform 1c
NCBI Official Synonym Full Names
ATPase secretory pathway Ca2+ transporting 1
NCBI Official Symbol
ATP2C1
NCBI Official Synonym Symbols
HHD; BCPM; PMR1; SPCA1; hSPCA1; ATP2C1A
UniProt Protein Name
Calcium-transporting ATPase type 2C member 1
UniProt Synonym Protein Names
ATP-dependent Ca(2+) pump PMR1
Protein Family
Calcium-transporting ATPase
UniProt Gene Name
ATP2C1
UniProt Synonym Gene Names
KIAA1347; PMR1L; ATPase 2C1
NCBI Protein Information
calcium-transporting ATPase type 2C member 1

NCBI Summary for ATP2C1

The protein encoded by this gene belongs to the family of P-type cation transport ATPases. This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium ions. Defects in this gene cause Hailey-Hailey disease, an autosomal dominant disorder. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
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UniProt Comments for ATP2C1

This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of the calcium.

Research Articles on ATP2C1

1. Studies indicate that Darier disease (DD) is caused by mutations in the ATP2A2 gene, whereas the ATP2C1 gene is associated with Hailey-Hailey disease (HHD).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ATP2C1 antibody

 Reference Product  PubMed Publications
 ATP2C2 antibody  >8 publications with ATP2C1 and ATP2C2
 SOD2 antibody  >1 publications with ATP2C1 and SOD2

Pathways associated with anti-ATP2C1 antibody

 Products by Pathway  Pathway Diagram
 Ion Channel Transport Pathway antibodies  Ion Channel Transport Pathway Diagram
 Ion Transport By P-type ATPases Pathway antibodies  Ion Transport By P-type ATPases Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram

Diseases associated with anti-ATP2C1 antibody

 Disease Name  Pubmed Publications
 Pemphigus, Benign Familial Antibodies  >81 publications with ATP2C1 and Pemphigus, Benign Familial
 Nervous System Diseases Antibodies  >5 publications with ATP2C1 and Nervous System Diseases
 Death Antibodies  >5 publications with ATP2C1 and Death
 Carcinoma Antibodies  >4 publications with ATP2C1 and Carcinoma
 Breast Neoplasms Antibodies  >2 publications with ATP2C1 and Breast Neoplasms
 Cardiovascular Diseases Antibodies  >2 publications with ATP2C1 and Cardiovascular Diseases
 Esophageal Neoplasms Antibodies  >1 publications with ATP2C1 and Esophageal Neoplasms
 Cell Transformation, Neoplastic Antibodies  >1 publications with ATP2C1 and Cell Transformation, Neoplastic
 Immune System Diseases Antibodies  >1 publications with ATP2C1 and Immune System Diseases
 Liver Diseases Antibodies  >1 publications with ATP2C1 and Liver Diseases

Organs/Tissues associated with anti-ATP2C1 antibody

 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >60 publications with ATP2C1 and Skin
 Blood Antibodies  >9 publications with ATP2C1 and Blood
 Brain Antibodies  >8 publications with ATP2C1 and Brain
 Mammary Gland Antibodies  >6 publications with ATP2C1 and Mammary Gland
 Muscle Antibodies  >6 publications with ATP2C1 and Muscle
 Liver Antibodies  >4 publications with ATP2C1 and Liver
 Lung Antibodies  >3 publications with ATP2C1 and Lung
 Vascular Antibodies  >3 publications with ATP2C1 and Vascular
 Pancreas Antibodies  >3 publications with ATP2C1 and Pancreas
 Heart Antibodies  >2 publications with ATP2C1 and Heart
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