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SRA Antibody – Mouse

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS850673

Steroid receptor RNA activator 1 (SRA), with 237-amino acid protein (about 27kDa), belongs to the growing family of functional non-coding RNAs. SRA was originally described as the first functional noncoding RNA able to specifically coactivate the activity of… More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SRA, Antibody
Full Product Name
SRA Antibody
Product Gene Name
Product Synonym Names
SRAP; STRAA1
Isotype
IgG1
Clone Number
7H1G1
Host
Mouse
Species Reactivity
Human
Form/Format
Ascitic fluid containing 0.03% sodium azide.
Preparation and Storage
Store at 4 degree C, for long term storage, store at-20 degree C
Molecular Weight
25,673 Da
OMIM
603819
3D Structure
ModBase 3D Structure for Q9HD15
Immunogen
Purified recombinant fragment of SRA expressed in E. Coli.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-SRA antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-SRA antibody
WB: 1:500-1:2000
IHC: 1:200-1:1000
ELISA: 1:10000

Western Blot (WB) of anti-SRA antibody

Figure 1. Western blot analysis using SRA mouse mAb against truncated SRA recombinant protein (1) and human ovary cancer tissue lysate (2).
Mouse Anti-SRA Antibody – Cat# MBS850673

Immunohistochemistry (IHC) of anti-SRA antibody

Figure 2. Immunohistochemical analysis of paraffin-embedded human bladder carcinoma (left) and breast carcinoma (right), showing nuclear and cytoplasmic localization using SRA mouse mAb with DAB staining.
Mouse Anti-SRA Antibody, Immunohistochemistry (IHC) – Cat# MBS850673

Other Notes

Small volumes of anti-SRA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SRA purchase

MBS850673 is an antibody targeting SRA. Also known as SRA Antibody. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for SRA. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
steroid receptor RNA activator 1 isoform 1
NCBI Official Synonym Full Names
steroid receptor RNA activator 1
NCBI Official Symbol
SRA1
NCBI Official Synonym Symbols
SRA; SRAP; STRAA1; pp7684
UniProt Protein Name
Steroid receptor RNA activator 1
UniProt Synonym Protein Names
Steroid receptor RNA activator protein; SRAP
Protein Family
UniProt Gene Name
SRA1
UniProt Synonym Gene Names
SRAP
NCBI Protein Information
steroid receptor RNA activator 1

NCBI Summary for SRA

Both long non-coding and protein-coding RNAs are transcribed from this gene, and they represent alternatively spliced transcript variants. This gene was initially defined as a non-coding RNA, which is a coactivator for several nuclear receptors (NRs) and is associated with breast cancer. It has now been found that this gene is involved in the regulation of many NR and non-NR activities, including metabolism, adipogenesis and chromatin organization. The long non-coding RNA transcripts interact with a variety of proteins, including the protein encoded by this gene. The encoded protein acts as a transcriptional repressor by binding to the non-coding RNA. [provided by RefSeq, Mar 2012]
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UniProt Comments for SRA

Functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N-terminal domain (AF-1) of steroid receptors. Also mediates transcriptional coactivation of steroid receptors ligand-dependently through the steroid-binding domain (AF-2). Enhances cellular proliferation and differentiation and promotes apoptosis in vivo. May play a role in tumorigenesis.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SRA antibody

 Reference Product  PubMed Publications
 NCOA1 antibody  >1 publications with SRA and NCOA1
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