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Neuropilin-1 (NRP1) Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS850768

Neuropilin-1 is a single-pass type I membrane protein, which has two isoforms. The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Neuropilin-1 (Nrp1), Antibody
Full Product Name
Neuropilin-1 Antibody
Product Gene Name
Clone Number
10-D9
Species Reactivity
Mouse
Form/Format
In 1*TBS (pH7.4), 0.5%BSA, 25%Glycerol.
Specificity
This antibody is produced by immunizing mouse with recombinant protein Neuropilin-1.
Preparation and Storage
Store at +4 degree C after thawing. Aliquot store at-20 degree C or-80 degree C. Avoid repeated freeze/thaw cycles.
Molecular Weight
47kDa
3D Structure
ModBase 3D Structure for P97333
Preservative
0.05% Sodium Azide.
Cellular Localization
Cell Membrane; Secretory Protein
Positive Control
Recombinant protein
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-Nrp1 antibody
Western Blot (WB), Immunocytochemistry (ICC)
Application Notes for anti-Nrp1 antibody
WB: 1:1,000~1:2,000
ICC: 1:100~1:200

Testing Data of anti-Nrp1 antibody

Anti-NRP1 Antibody – Cat# MBS850768

Product References and Citations for anti-Nrp1 antibody

1. "Neuropilin-2 and neuropilin-1 are receptors for the 165-amino acid form of vascular endothelial growth factor (VEGF) and of placenta growth factor-2, but only neuropilin-2 functions as a receptor for the 145-amino acid form of VEGF."Gluzman-Poltorak Z., Cohen T., Herzog Y., Neufeld G.J. Biol. Chem. 275:18040-18045(2000). 2. "Neuropilin is a receptor for the axonal chemorepellent semaphorin III."He Z., Tessier-Lavigne M.Cell 90:739-751(1997).

Other Notes

Small volumes of anti-Nrp1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Nrp1 purchase

MBS850768 is an antibody targeting Nrp1. Also known as Neuropilin-1 Antibody. Reactive in Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for Nrp1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
neuropilin-1 isoform 1
NCBI Official Synonym Full Names
neuropilin 1
NCBI Official Symbol
Nrp1
NCBI Official Synonym Symbols
Nrp; NP-1; Npn1; NPN-1; C530029I03
UniProt Protein Name
Neuropilin-1
UniProt Synonym Protein Names
A5 protein; CD_antigen: CD304
Protein Family
UniProt Gene Name
Nrp1
UniProt Synonym Gene Names
Nrp
NCBI Protein Information
neuropilin-1

UniProt Comments for Nrp1

Receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. Mediates the chemorepulsant activity of semaphorins. Binds to semaphorin 3A, the PLGF-2 isoform of PGF, the VEGF165 isoform of VEGFA and VEGFB. Coexpression with KDR results in increased VEGF165 binding to KDR as well as increased chemotaxis. Regulates VEGF-induced angiogenesis (). Binding to VEGFA initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (PubMed:26503042).
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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