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PFKFB2 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS851024

MBS851024 is an antibody targeting PFKFB2. Also known as PFKFB2 Antibody. Reactive in Human. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PFKFB2, Antibody
Full Product Name
PFKFB2 Antibody
Product Gene Name
Product Synonym Names
6-phosphofructo-2-kinase; 6-phosphofructo-2-kinase/fructose-2; 6-biphosphatase 2; 6PF-2-K/Fru-2; 6-P2ase heart-type isozyme; F262; PFK-2/FBPase-2; PFK-2/FBPase-2; heart type; fructose-2; 6-bisphosphatas
Species Reactivity
Human
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
PFKFB2 detects endogenous levels of total PFKFB2 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
54,406 Da
OMIM
171835
3D Structure
ModBase 3D Structure for O60825
Immunogen
The antiserum was produced against synthesized peptide derived from N-terminal of human PFKFB2.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-PFKFB2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-PFKFB2 antibody
WB: 1:500~1:1000
ELISA: 1:20000

Western Blot (WB) of anti-PFKFB2 antibody

Western blot analysis of extracts from Jurkat cells, using PFKFB2 antibody.
Anti-PFKFB2 Antibody – Cat# MBS851024

Product References and Citations for anti-PFKFB2 antibody

Heine-Suner D., Eur. J. Biochem. 254:103-110(1998). Soejima H., Genomics 74:115-120(2001). Gregory S.G., Nature 441:315-321(2006).

Other Notes

Small volumes of anti-PFKFB2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PFKFB2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 isoform b
NCBI Official Synonym Full Names
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
NCBI Official Symbol
PFKFB2
NCBI Official Synonym Symbols
PFK-2/FBPase-2
UniProt Protein Name
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2
UniProt Synonym Protein Names
6PF-2-K/Fru-2,6-P2ase heart-type isozymeIncluding the following 2 domains:6-phosphofructo-2-kinase (EC:2.7.1.105)Fructose-2,6-bisphosphatase (EC:3.1.3.46)
UniProt Gene Name
PFKFB2
UniProt Synonym Gene Names
6PF-2-K/Fru-2,6-P2ase 2; PFK/FBPase 2
NCBI Protein Information
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2

NCBI Summary for PFKFB2

The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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UniProt Comments for PFKFB2

Synthesis and degradation of fructose 2,6-bisphosphate.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-PFKFB2 antibody

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