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GPR75 Antibody – Rabbit

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS851084

MBS851084 is an antibody targeting GPR75. Also known as GPR75 Antibody. Reactive in Human, Mouse. Host: Rabbit. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GPR75, Antibody
Full Product Name
GPR75 Antibody
Product Gene Name
Product Synonym Names
Probable G-protein coupled receptor 75; GPR75
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
GPR75 antibody detects endogenous levels of total GPR75 protein.
Preparation and Storage
Store at -20°C for 1 year.
Molecular Weight
59,359 Da
OMIM
606704
3D Structure
ModBase 3D Structure for O95800
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human GPR75.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-GPR75 antibody
Western Blot (WB), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-GPR75 antibody
WB: 1:500~1:1000
IF: 1:100~1:500
ELISA: 1:5000

Western Blot (WB) of anti-GPR75 antibody

Western blot analysis of extracts from HT-29 cells and K562 cells, using GPR75 antibody.
Rabbit Anti-GPR75 Antibody – Cat# MBS851084

Immunofluoresence (IF) of anti-GPR75 antibody

Immunofluorescence analysis of LOVO cells, using GPR75 antibody.
Rabbit Anti-GPR75 Antibody, Immunofluoresence (IF) – Cat# MBS851084

Product References and Citations for anti-GPR75 antibody

Tarttelin E.E., Biochem. Biophys. Res. Commun. 260:174-180(1999). Hillier L.W., Nature 434:724-731(2005). The MGC Project Team; Genome Res. 14:2121-2127(2004).

Other Notes

Small volumes of anti-GPR75 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GPR75. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
probable G-protein coupled receptor 75
NCBI Official Synonym Full Names
G protein-coupled receptor 75
NCBI Official Symbol
GPR75
NCBI Official Synonym Symbols
GPRchr2; WI31133
UniProt Protein Name
Probable G-protein coupled receptor 75
UniProt Gene Name
GPR75
NCBI Protein Information
probable G-protein coupled receptor 75

NCBI Summary for GPR75

GPR75 is a member of the G protein-coupled receptor family. GPRs are cell surface receptors that activate guanine-nucleotide binding proteins upon the binding of a ligand.[supplied by OMIM, Jul 2002]

UniProt Comments for GPR75

G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-GPR75 antibody

Diseases associated with anti-GPR75 antibody

 Disease Name  Pubmed Publications
 Eye Diseases Antibodies  >2 publications with GPR75 and Eye Diseases
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