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MC5R Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS851144

MBS851144 is an antibody targeting MC5R. Also known as MC5R Antibody. Reactive in Human, Mouse, Rat. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MC5R, Antibody
Full Product Name
MC5R Antibody
Product Gene Name
anti-MC5R antibody
Product Synonym Names
MC-2; MC5-R; melanocortin 5 receptor; melanocortin receptor 5
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
MC5R antibody detects endogenous levels of total MC5R protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
36,601 Da
OMIM
600042
3D Structure
ModBase 3D Structure for P33032
Immunogen
The antiserum was produced against synthesized peptide derived from C-terminal of human MC5R.

Product Categories/Family for anti-MC5R antibody

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-MC5R antibody
Western Blot (WB), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-MC5R antibody
WB: 1:500~1:1000
IF: 1:100~1:500
ELISA: 1:40000

Testing Data of anti-MC5R antibody

Anti-MC5R Antibody – Cat# MBS851144

Western Blot (WB) of anti-MC5R antibody

Peptide-+ Western blot analysis of extracts from K562 cells, using MC5R antibody. Immunofluorescence analysis of MCF-7 cells, using MC5R antibody.
Anti-MC5R Antibody, Western Blot (WB) – Cat# MBS851144

Product References and Citations for anti-MC5R antibody

Chhajlani V., Biochem. Biophys. Res. Commun. 195:866-873(1993). Griffon N., Biochem. Biophys. Res. Commun. 200:1007-1014(1994). Fathi Z., Neurochem. Res. 20:107-113(1995).

Other Notes

Small volumes of anti-MC5R antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MC5R. It may not necessarily be applicable to this product.

NCBI GI #
5174535
NCBI GeneID
4161
NCBI Accession #
NP_005904.1
UniProt Primary Accession #
P33032
UniProt Secondary Accession #
Q502V1; B0YJ34
UniProt Related Accession #
P33032
GenBank Nucleotide #
NM_005913.2
NCBI Official Full Name
melanocortin receptor 5
NCBI Official Synonym Full Names
melanocortin 5 receptor
NCBI Official Symbol
MC5R
NCBI Official Synonym Symbols
MC2
UniProt Protein Name
Melanocortin receptor 5
UniProt Synonym Protein Names
MC-2
Protein Family
Melanocortin receptor
UniProt Gene Name
MC5R
UniProt Synonym Gene Names
MC5-R
NCBI Protein Information
melanocortin receptor 5

NCBI Summary for MC5R

This gene encodes a member of the seven-pass transmembrane G protein-coupled melanocortin receptor protein family that stimulate cAMP signal transduction. The encoded protein is a receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone and is suggested to play a role in sebum generation. [provided by RefSeq, Jun 2010]
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UniProt Comments for MC5R

Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins.

Research Articles on MC5R

1. Mutations in residues S4/S5 and S17/E18 retained MC5R at the ER/Golgi complex and did not affect MC5R homodimerization.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-MC5R antibody

 Reference Product  PubMed Publications
 POMC antibody  >84 publications with MC5R and POMC
 AGRP antibody  >10 publications with MC5R and AGRP
 ASIP antibody  >2 publications with MC5R and ASIP

Pathways associated with anti-MC5R antibody

 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Peptide GPCRs Pathway antibodies  Peptide GPCRs Pathway Diagram
 Peptide Ligand-binding Receptors Pathway antibodies  Peptide Ligand-binding Receptors Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram

Diseases associated with anti-MC5R antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >7 publications with MC5R and Inflammation
 Mental Disorders Antibodies  >3 publications with MC5R and Mental Disorders
 Hypertension Antibodies  >3 publications with MC5R and Hypertension
 Pain Antibodies  >3 publications with MC5R and Pain
 Drug Toxicity Antibodies  >3 publications with MC5R and Drug Toxicity
 Insulin Resistance Antibodies  >2 publications with MC5R and Insulin Resistance
 Learning Disorders Antibodies  >2 publications with MC5R and Learning Disorders
 Skin Diseases Antibodies  >2 publications with MC5R and Skin Diseases
 Lung Diseases Antibodies  >1 publications with MC5R and Lung Diseases
 Fever Antibodies  >1 publications with MC5R and Fever

Organs/Tissues associated with anti-MC5R antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >40 publications with MC5R and Brain
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