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RASD2 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS851206

MBS851206 is an antibody targeting RASD2. Also known as RASD2 Antibody. Reactive in Human, Mouse, Rat. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RASD2, Antibody
Full Product Name
RASD2 Antibody
Product Gene Name
Product Synonym Names
GTP-binding protein Rhes; Ras homolog enriched in striatum; Tumor endothelial marker 2; RASD2; TEM2
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
RASD2 antibody detects endogenous levels of total RASD2 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
30,366 Da
OMIM
612842
3D Structure
ModBase 3D Structure for Q96D21
Immunogen
The antiserum was produced against synthesized peptide derived from C-terminal of human RASD2.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-RASD2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-RASD2 antibody
WB: 1:500~1:1000
ELISA: 1:40000

Western Blot (WB) of anti-RASD2 antibody

Western blot analysis of extracts from Jurkat cells, using RASD2 antibody.
Anti-RASD2 Antibody – Cat# MBS851206

Product References and Citations for anti-RASD2 antibody

St Croix B., Science 289:1197-1202(2000). Collins J.E., Genome Biol. 5:R84.1-R84.11(2004). Dunham I., Nature 402:489-495(1999).

Other Notes

Small volumes of anti-RASD2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RASD2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
GTP-binding protein Rhes
NCBI Official Synonym Full Names
RASD family member 2
NCBI Official Symbol
RASD2
NCBI Official Synonym Symbols
Rhes; TEM2; MGC:4834
UniProt Protein Name
GTP-binding protein Rhes
UniProt Synonym Protein Names
Ras homolog enriched in striatum; Tumor endothelial marker 2
Protein Family
UniProt Gene Name
RASD2
UniProt Synonym Gene Names
TEM2
NCBI Protein Information
GTP-binding protein Rhes

NCBI Summary for RASD2

This gene belongs to the Ras superfamily of small GTPases and is enriched in the striatum. The encoded protein functions as an E3 ligase for attachment of small ubiquitin-like modifier (SUMO). This protein also binds to mutant huntingtin (mHtt), the protein mutated in Huntington disease (HD). Sumoylation of mHTT by this protein may cause degeneration of the striatum. The protein functions as an activator of mechanistic target of rapamycin 1 (mTOR1), which in turn plays a role in myelination, axon growth and regeneration. Reduced levels of mRNA expressed by this gene were found in HD patients. [provided by RefSeq, Jan 2016]
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UniProt Comments for RASD2

GTPase signaling protein that binds to and hydrolyzes GTP. Regulates signaling pathways involving G-proteins-coupled receptor and heterotrimeric proteins such as GNB1, GNB2 and GNB3. May be involved in selected striatal competencies, mainly locomotor activity and motor coordination.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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