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BORG3 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS851225

MBS851225 is an antibody targeting BORG3. Also known as BORG3 Antibody. Reactive in Human, Mouse. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
BORG3, Antibody
Full Product Name
BORG3 Antibody
Product Gene Name
Product Synonym Names
binder of Rho GTPases 3; Borg3; Cdc42 effector 5; CEP5
Species Reactivity
Human, Mouse
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
BORG3 antibody detects endogenous levels of total BORG3 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
15,207 Da
OMIM
609171
3D Structure
ModBase 3D Structure for Q6NZY7
Immunogen
The antiserum was produced against synthesized peptide derived from N-terminal of human BORG3.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-BORG3 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-BORG3 antibody
WB: 1:500~1:1000
ELISA: 1:40000

Western Blot (WB) of anti-BORG3 antibody

Western blot analysis of extracts from Jurkat cells, using BORG3 antibody.
Anti-BORG3 Antibody – Cat# MBS851225

Product References and Citations for anti-BORG3 antibody

The MGC Project Team; Genome Res. 14:2121-2127(2004).

Other Notes

Small volumes of anti-BORG3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for BORG3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cdc42 effector protein 5
NCBI Official Synonym Full Names
CDC42 effector protein 5
NCBI Official Symbol
CDC42EP5
NCBI Official Synonym Symbols
CEP5; Borg3
UniProt Protein Name
Cdc42 effector protein 5
UniProt Synonym Protein Names
Binder of Rho GTPases 3
UniProt Gene Name
CDC42EP5
UniProt Synonym Gene Names
BORG3; CEP5
NCBI Protein Information
cdc42 effector protein 5

NCBI Summary for BORG3

Cell division control protein 42 (CDC42), a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg (binder of Rho GTPases) family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to CDC42 and regulate its function negatively. The encoded protein may inhibit c-Jun N-terminal kinase (JNK) independently of CDC42 binding. The protein may also play a role in septin organization and inducing pseudopodia formation in fibroblasts [provided by RefSeq, Jul 2013]
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UniProt Comments for BORG3

Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts. Inhibits MAPK8 independently of CDC42 binding. Controls septin organization and this effect is negatively regulated by CDC42 ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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