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BCOR Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS851295

MBS851295 is an antibody targeting BCOR. Also known as BCOR Antibody. Reactive in Human, Mouse. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
BCOR, Antibody
Full Product Name
BCOR Antibody
Product Gene Name
Product Synonym Names
BCL-6 corepressor; BCoR; BCOR; KIAA1575
Species Reactivity
Human, Mouse
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
BCOR antibody detects endogenous levels of total BCOR protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
186,235 Da
OMIM
300166
3D Structure
ModBase 3D Structure for Q6W2J9
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human BCOR.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-BCOR antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-BCOR antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:20000

Testing Data of anti-BCOR antibody

Peptide-+
Anti-BCOR Antibody – Cat# MBS851295

Immunohistochemistry (IHC) of anti-BCOR antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using BCOR antibody. Western blot analysis of extracts from COLO cells, using BCOR antibody.
Anti-BCOR Antibody, Immunohistochemistry (IHC) – Cat# MBS851295

Product References and Citations for anti-BCOR antibody

Huynh K.D., Genes Dev. 14:1810-1823(2000). Ng D., Nat. Genet. 36:411-416(2004). Nagase T., DNA Res. 7:273-281(2000).

Other Notes

Small volumes of anti-BCOR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for BCOR. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
BCL-6 corepressor isoform a
NCBI Official Synonym Full Names
BCL6 corepressor
NCBI Official Symbol
BCOR
NCBI Official Synonym Symbols
MAA2; ANOP2; MCOPS2
UniProt Protein Name
BCL-6 corepressor
Protein Family
UniProt Gene Name
BCOR
UniProt Synonym Gene Names
KIAA1575; BCoR
NCBI Protein Information
BCL-6 corepressor

NCBI Summary for BCOR

The protein encoded by this gene was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs. Several transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome Y.[provided by RefSeq, Jun 2010]
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UniProt Comments for BCOR

Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6 and MLLT3. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Involved in the repression of TFAP2A; impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells; the function implies inhibition of methylation on histone H3 'Lys-4' (H3K4me3) and 'Lys-36' (H3K36me2).
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-BCOR antibody

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