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EFNA2 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS851343

MBS851343 is an antibody targeting EFNA2. Also known as EFNA2 Antibody. Reactive in Human, Mouse. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
EFNA2, Antibody
Full Product Name
EFNA2 Antibody
Product Gene Name
Product Synonym Names
Ephrin-A2 [Precursor]; EPH-related receptor tyrosine kinase ligand 6; LERK-6; HEK7-ligand; HEK7-L; EFNA2; EPLG6; LERK6
Species Reactivity
Human, Mouse
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
EFNA2 antibody detects endogenous levels of total EFNA2 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
23,878 Da
OMIM
602756
3D Structure
ModBase 3D Structure for O43921
Immunogen
The antiserum was produced against synthesized peptide derived from Internal of human EFNA2.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-EFNA2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-EFNA2 antibody
WB: 1:500~1:1000
ELISA: 1:5000

Western Blot (WB) of anti-EFNA2 antibody

Western blot analysis of extracts from COLO205 cells and HeLa cells, using EFNA2 antibody.
Anti-EFNA2 Antibody – Cat# MBS851343

Product References and Citations for anti-EFNA2 antibody

Cerretti D.P., Genomics 47:131-135(1998). Aasheim H.C., Biochem. Biophys. Res. Commun. 252:378-382(1998). Grimwood J., Nature 428:529-535(2004).

Other Notes

Small volumes of anti-EFNA2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for EFNA2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
ephrin-A2
NCBI Official Synonym Full Names
ephrin A2
NCBI Official Symbol
EFNA2
NCBI Official Synonym Symbols
ELF-1; EPLG6; LERK6; HEK7-L; LERK-6
UniProt Protein Name
Ephrin-A2
UniProt Synonym Protein Names
EPH-related receptor tyrosine kinase ligand 6; LERK-6; HEK7 ligand; HEK7-L
Protein Family
UniProt Gene Name
EFNA2
UniProt Synonym Gene Names
EPLG6; LERK6; LERK-6; HEK7-L
NCBI Protein Information
ephrin-A2

NCBI Summary for EFNA2

This gene encodes a member of the ephrin family. The protein is composed of a signal sequence, a receptor-binding region, a spacer region, and a hydrophobic region. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Posttranslational modifications determine whether this protein localizes to the nucleus or the cytoplasm. [provided by RefSeq, Jul 2008]
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UniProt Comments for EFNA2

Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. With the EPHA2 receptor may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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