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FZD10 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS851387

MBS851387 is an antibody targeting FZD10. Also known as FZD10 Antibody. Reactive in Human, Mouse. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
FZD10, Antibody
Full Product Name
FZD10 Antibody
Product Gene Name
Product Synonym Names
Frizzled-10 [Precursor]; Fz-10; hFz10; FzE7; CD350 antigen; FZD10
Species Reactivity
Human, Mouse
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
FZD10 antibody detects endogenous levels of total FZD10 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
65,336 Da
OMIM
606147
3D Structure
ModBase 3D Structure for Q9ULW2
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human FZD10.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-FZD10 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-FZD10 antibody
WB: 1:500~1:1000
ELISA: 1:5000

Western Blot (WB) of anti-FZD10 antibody

Western blot analysis of extracts from COS-7 cells, using FZD10 antibody.
Anti-FZD10 Antibody – Cat# MBS851387

Product References and Citations for anti-FZD10 antibody

Koike J., Biochem. Biophys. Res. Commun. 262:39-43(1999). The MGC Project Team; Genome Res. 14:2121-2127(2004). Tanaka S., Proc. Natl. Acad. Sci. U.S.A. 95:10164-10169(1998).

Other Notes

Small volumes of anti-FZD10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for FZD10. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
frizzled-10
NCBI Official Synonym Full Names
frizzled class receptor 10
NCBI Official Symbol
FZD10
NCBI Official Synonym Symbols
Fz10; FzE7; CD350; FZ-10; hFz10
UniProt Protein Name
Frizzled-10
UniProt Synonym Protein Names
FzE7; CD_antigen: CD350
Protein Family
UniProt Gene Name
FZD10
UniProt Synonym Gene Names
Fz-10; hFz10
NCBI Protein Information
frizzled-10

NCBI Summary for FZD10

This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer. [provided by RefSeq, Jul 2008]
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UniProt Comments for FZD10

Receptor for Wnt proteins. Functions in the canonical Wnt/beta-catenin signaling pathway (). The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues (Probable).
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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