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IKZF3 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS851438

MBS851438 is an antibody targeting IKZF3. Also known as IKZF3 Antibody. Reactive in Human, Mouse. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IKZF3, Antibody
Full Product Name
IKZF3 Antibody
Product Gene Name
Product Synonym Names
AIOL; IKZF3; ZNFN1A3; zinc finger protein Aiolos
Species Reactivity
Human, Mouse
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
IKZF3 antibody detects endogenous levels of total IKZF3 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
29,973 Da
OMIM
606221
3D Structure
ModBase 3D Structure for Q9UKT9
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human IKZF3.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-IKZF3 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-IKZF3 antibody
WB: 1:500-1:1000
ELISA: 1:10000

Western Blot (WB) of anti-IKZF3 antibody

Western blot analysis of extracts from COLO cells, using IKZF3 antibody.
Anti-IKZF3 Antibody – Cat# MBS851438

Product References and Citations for anti-IKZF3 antibody

Hosokawa Y., Genomics 61:326-329(1999). Liippo J.P., Eur. J. Immunol. 31:3469-3474(2001). Perdomo J., J. Biol. Chem. 275:38347-38354(2000).

Other Notes

Small volumes of anti-IKZF3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IKZF3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
zinc finger protein Aiolos isoform 7
NCBI Official Synonym Full Names
IKAROS family zinc finger 3
NCBI Official Symbol
IKZF3
NCBI Official Synonym Symbols
AIO; AIOLOS; ZNFN1A3
UniProt Protein Name
Zinc finger protein Aiolos
UniProt Synonym Protein Names
Ikaros family zinc finger protein 3
Protein Family
UniProt Gene Name
IKZF3
UniProt Synonym Gene Names
ZNFN1A3
NCBI Protein Information
zinc finger protein Aiolos

NCBI Summary for IKZF3

This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. [provided by RefSeq, Apr 2012]
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UniProt Comments for IKZF3

Transcription factor that plays an important role in the regulation of lymphocyte differentiation. Plays an essential role in regulation of B-cell differentiation, proliferation and maturation to an effector state. Involved in regulating BCL2 expression and controlling apoptosis in T-cells in an IL2-dependent manner.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-IKZF3 antibody

Pathways associated with anti-IKZF3 antibody

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