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KCNMB2 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS851545

MBS851545 is an antibody targeting KCNMB2. Also known as KCNMB2 Antibody. Reactive in Human, Mouse, Rat. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
KCNMB2, Antibody
Full Product Name
KCNMB2 Antibody
Product Gene Name
Product Synonym Names
BK channel beta-2; BKbeta2; calcium-activated potassium channel beta-2; calcium-activated potassium channel, subfamily M beta-2; charybdotoxin receptor beta-2; Hbeta2; Hbeta3; K(VCA)beta-2; KCMB2; maxi K channel beta-2; potassium large conductance calcium-activated channel, subfamily M, beta member 2; Slo-beta-2
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
KCNMB2 antibody detects endogenous levels of total KCNMB2 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
27,130 Da
OMIM
605214
3D Structure
ModBase 3D Structure for Q9Y691
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human KCNMB2.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-KCNMB2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-KCNMB2 antibody
WB: 1:500~1:1000
ELISA: 1:20000

Western Blot (WB) of anti-KCNMB2 antibody

Western blot analysis of extracts from HepG2 cells, COLO cells and Jurkat cells, using KCNMB2 antibody.
Anti-KCNMB2 Antibody – Cat# MBS851545

Product References and Citations for anti-KCNMB2 antibody

Wallner M., Proc. Natl. Acad. Sci. U.S.A. 96:4137-4142(1999). Brenner R., J. Biol. Chem. 275:6453-6461(2000). The MGC Project Team; Genome Res. 14:2121-2127(2004).

Other Notes

Small volumes of anti-KCNMB2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for KCNMB2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
calcium-activated potassium channel subunit beta-2
NCBI Official Synonym Full Names
potassium calcium-activated channel subfamily M regulatory beta subunit 2
NCBI Official Symbol
KCNMB2
UniProt Protein Name
Calcium-activated potassium channel subunit beta-2
UniProt Synonym Protein Names
BK channel subunit beta-2; BKbeta2; Hbeta2; Calcium-activated potassium channel, subfamily M subunit beta-2; Charybdotoxin receptor subunit beta-2; Hbeta3; K(VCA)beta-2; Maxi K channel subunit beta-2; Slo-beta-2
UniProt Gene Name
KCNMB2
UniProt Synonym Gene Names
BKbeta2; Hbeta2
NCBI Protein Information
calcium-activated potassium channel subunit beta-2

NCBI Summary for KCNMB2

MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which decreases the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants of this gene. Additional variants are discussed in the literature, but their full length nature has not been described. [provided by RefSeq, Jul 2013]
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UniProt Comments for KCNMB2

Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Acts as a negative regulator that confers rapid and complete inactivation of KCNMA1 channel complex. May participate in KCNMA1 inactivation in chromaffin cells of the adrenal gland or in hippocampal CA1 neurons.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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