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PTGDR Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS851570

MBS851570 is an antibody targeting PTGDR. Also known as PTGDR Antibody. Reactive in Human. Host: Rabbit. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PTGDR, Polyclonal Antibody
Full Product Name
PTGDR Antibody
Product Gene Name
anti-PTGDR antibody
Product Synonym Names
Prostaglandin D2 receptor; Prostanoid DP receptor; PGD receptor
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
PTGDR antibody detects endogenous levels of total PTGDR protein.
Preparation and Storage
Store at-20 degree C for 1 year.
OMIM
604687
3D Structure
ModBase 3D Structure for Q13258
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human PTGDR.

Product Categories/Family for anti-PTGDR antibody

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-PTGDR antibody
Western Blot (WB), Immunofluorescence (IF), ELISA
Application Notes for anti-PTGDR antibody
WB: 1:500~1:1000
IF: 1:100~1:500
ELISA: 1:40000

Western Blot (WB) of anti-PTGDR antibody

Peptide: - / +
Western blot analysis of extracts from HepG2 cells, using PTGDR antibody.
Rabbit Anti-PTGDR Polyclonal Antibody – Cat# MBS851570

Immunohistochemistry (IHC) of anti-PTGDR antibody

Peptide: - / +
Immunofluorescence analysis of A549 cells, using PTGDR antibody.
Rabbit Anti-PTGDR Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS851570

Product References and Citations for anti-PTGDR antibody

Boie Y., J. Biol. Chem. 270:18910-18916(1995). The MGC Project Team; Genome Res. 14:2121-2127(2004). Oguma T., N. Engl. J. Med. 351:1752-1763(2004).

Other Notes

Small volumes of anti-PTGDR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PTGDR. It may not necessarily be applicable to this product.

NCBI GI #
28466969
NCBI GeneID
5729
NCBI Accession #
NP_000944.1
UniProt Primary Accession #
Q13258
UniProt Secondary Accession #
Q13250; Q13251; Q1ZZ52; G3V5L3
UniProt Related Accession #
Q13258
GenBank Nucleotide #
NM_000953.2
NCBI Official Full Name
prostaglandin D2 receptor isoform 1
NCBI Official Synonym Full Names
prostaglandin D2 receptor
NCBI Official Symbol
PTGDR
NCBI Official Synonym Symbols
DP; AS1; DP1; ASRT1; PTGDR1
UniProt Protein Name
Prostaglandin D2 receptor
UniProt Synonym Protein Names
Prostanoid DP receptor
Protein Family
Prostaglandin D2 receptor
UniProt Gene Name
PTGDR
UniProt Synonym Gene Names
PGD receptor; PGD2 receptor
NCBI Protein Information
prostaglandin D2 receptor

NCBI Summary for PTGDR

This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein is reported to be a receptor for prostaglandin D2, which is a mediator of allergic inflammation and allergic airway inflammation in asthma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
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UniProt Comments for PTGDR

Receptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate ().

Research Articles on PTGDR

1. Polymorphisms of prostaglandin D receptor (PTGDR) gene influence basal promoter activity and gene expression, as well as the cytokine secretory pattern.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-PTGDR antibody

 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Eicosanoid Ligand-binding Receptors Pathway antibodies  Eicosanoid Ligand-binding Receptors Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Prostaglandin Synthesis And Regulation Pathway antibodies  Prostaglandin Synthesis And Regulation Pathway Diagram
 Prostanoid Ligand Receptors Pathway antibodies  Prostanoid Ligand Receptors Pathway Diagram

Diseases associated with anti-PTGDR antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >4 publications with PTGDR and Inflammation
 Carcinoma Antibodies  >2 publications with PTGDR and Carcinoma
 Cardiovascular Diseases Antibodies  >2 publications with PTGDR and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >2 publications with PTGDR and Disease Models, Animal
 Flushing Antibodies  >1 publications with PTGDR and Flushing
 Atherosclerosis Antibodies  >1 publications with PTGDR and Atherosclerosis
 Hyperplasia Antibodies  >1 publications with PTGDR and Hyperplasia
 Necrosis Antibodies  >1 publications with PTGDR and Necrosis
 ASTHMA-RELATED TRAITS, SUSCEPTIBILITY TO, 1 Antibodies  >1 publications with PTGDR and ASTHMA-RELATED TRAITS, SUSCEPTIBILITY TO, 1

Organs/Tissues associated with anti-PTGDR antibody

 Organ/Tissue Name  Pubmed Publications
 Uterus Antibodies  >1 publications with PTGDR and Uterus
 Liver Antibodies  >1 publications with PTGDR and Liver
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