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LRAT Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS851607

MBS851607 is an antibody targeting LRAT. Also known as LRAT Antibody. Reactive in Human, Mouse, Rat. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
LRAT, Antibody
Full Product Name
LRAT Antibody
Product Gene Name
Product Synonym Names
Lecithin retinol acyltransferase; EC 2.3.1.135; Phosphatidylcholine--retinol O-acyltransferase; LRAT
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
LRAT antibody detects endogenous levels of total LRAT protein.
Preparation and Storage
Store at -20°C for 1 year.
OMIM
604863
3D Structure
ModBase 3D Structure for O95237
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human LRAT.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-LRAT antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-LRAT antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
IF: 1:100~1:500
ELISA: 1:10000

Testing Data of anti-LRAT antibody

Peptide-+

Immunohistochemistry analysis of paraffin-embadded human prostate carcinoma tissue using LRAT antibody.
Anti-LRAT Antibody – Cat# MBS851607

Immunohistochemistry (IHC) of anti-LRAT antibody

Immunohistochemistry analysis of paraffin-embedded human prostate carcinoma tissue using LRAT antibody. Western blot analysis of extracts from COLO205 cells, using LRAT antibody.
Anti-LRAT Antibody, Immunohistochemistry (IHC) – Cat# MBS851607

Immunofluorescence (IF) of anti-LRAT antibody

Peptide-+ Immunofluorescence analysis of HUVEC cells, using LRAT antibody.
Anti-LRAT Antibody, Immunofluorescence (IF) – Cat# MBS851607

Product References and Citations for anti-LRAT antibody

Ruiz A., J. Biol. Chem. 274:3834-3841(1999). Mondal M.S., Biochemistry 39:5215-5220(2000). Thompson D.A., Nat. Genet. 28:123-124(2001).

Other Notes

Small volumes of anti-LRAT antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for LRAT. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
lecithin retinol acyltransferase
NCBI Official Synonym Full Names
lecithin retinol acyltransferase
NCBI Official Symbol
LRAT
NCBI Official Synonym Symbols
LCA14
UniProt Protein Name
Lecithin retinol acyltransferase
UniProt Synonym Protein Names
Phosphatidylcholine--retinol O-acyltransferase
UniProt Gene Name
LRAT
NCBI Protein Information
lecithin retinol acyltransferase

NCBI Summary for LRAT

The protein encoded by this gene localizes to the endoplasmic reticulum, where it catalyzes the esterification of all-trans-retinol into all-trans-retinyl ester. This reaction is an important step in vitamin A metabolism in the visual system. Mutations in this gene have been associated with early-onset severe retinal dystrophy and Leber congenital amaurosis 14. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]
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UniProt Comments for LRAT

Transfers the acyl group from the sn-1 position of phosphatidylcholine to all-trans retinol, producing all-trans retinyl esters. Retinyl esters are storage forms of vitamin A. LRAT plays a critical role in vision. It provides the all-trans retinyl ester substrates for the isomerohydrolase which processes the esters into 11-cis-retinol in the retinal pigment epithelium; due to a membrane-associated alcohol dehydrogenase, 11 cis-retinol is oxidized and converted into 11-cis-retinaldehyde which is the chromophore for rhodopsin and the cone photopigments.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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