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STK36 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS851617

MBS851617 is an antibody targeting STK36. Also known as STK36 Antibody. Reactive in Human, Mouse. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
STK36, Antibody
Full Product Name
STK36 Antibody
Product Gene Name
Product Synonym Names
Serine/threonine-protein kinase 36 EC 2.7.11.1; Fused homolog STK36
Species Reactivity
Human, Mouse
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
STK36 antibody detects endogenous levels of total STK36 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
141,737 Da
OMIM
607652
3D Structure
ModBase 3D Structure for Q9NRP7
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human STK36.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-STK36 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-STK36 antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:1000

Testing Data #3 of anti-STK36 antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using STK36 antibody.
Western blot analysis of extracts from K562 cells, using STK36 antibody.
Anti-STK36 Antibody – Cat# MBS851617

Product References and Citations for anti-STK36 antibody

Murone M., Nat. Cell Biol. 2:310-312(2000). Nagase T., DNA Res. 6:337-345(1999). Hillier L.W., Nature 434:724-731(2005).

Other Notes

Small volumes of anti-STK36 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for STK36. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
serine/threonine-protein kinase 36 isoform 2
NCBI Official Synonym Full Names
serine/threonine kinase 36
NCBI Official Symbol
STK36
NCBI Official Synonym Symbols
FU
UniProt Protein Name
Serine/threonine-protein kinase 36
UniProt Synonym Protein Names
Fused homolog
UniProt Gene Name
STK36
NCBI Protein Information
serine/threonine-protein kinase 36

NCBI Summary for STK36

This gene encodes a member of the serine/threonine kinase family of enzymes. This family member is similar to a Drosophila protein that plays a key role in the Hedgehog signaling pathway. This human protein is a positive regulator of the GLI zinc-finger transcription factors. Knockout studies of the homologous mouse gene suggest that defects in this human gene may lead to congenital hydrocephalus, possibly due to a functional defect in motile cilia. Because Hedgehog signaling is frequently activated in certain kinds of gastrointestinal cancers, it has been suggested that this gene is a target for the treatment of these cancers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]
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UniProt Comments for STK36

Serine/threonine protein kinase which plays an important role in the sonic hedgehog (Shh) pathway by regulating the activity of GLI transcription factors (PubMed:10806483). Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization (PubMed:10806483). GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur (PubMed:10806483). Required for postnatal development, possibly by regulating the homeostasis of cerebral spinal fluid or ciliary function (). Essential for construction of the central pair apparatus of motile cilia.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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