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PPGB Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS851667

MBS851667 is an antibody targeting PPGB. Also known as PPGB (32k, Cleaved-Arg326) Antibody. Reactive in Human, Mouse. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PPGB, Antibody
Full Product Name
PPGB (32k, Cleaved-Arg326) Antibody
Product Gene Name
Product Synonym Names
Lysosomal protective protein [Precursor]; EC 3.4.16.5; Cathepsin A; Carboxypeptidase C; Protective protein for beta-galactosidase; Lysosomal protective protein 32 kDa chain; Lysosomal protective protein 20 kDa chain; CTSA; PPGB
Species Reactivity
Human, Mouse
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
PPGB (32k, Cleaved-Arg326) antibody detects endogenous levels of fragment of activated PPGB resulting from cleavage adjacent to Arg326.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
52,489 Da
OMIM
256540
3D Structure
ModBase 3D Structure for P10619
Immunogen
The antiserum was produced against synthesized peptide derived from human PPGB.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-PPGB antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-PPGB antibody
WB: 1:500-1:1000
ELISA: 1:10000

Western Blot (WB) of anti-PPGB antibody

Western blot analysis of extracts from Jurkat cells and 293 cells, treated with etoposide (25uM, 1hour), using PPGB (32k, Cleaved-Arg326) antibody.
Anti-PPGB Antibody – Cat# MBS851667

Product References and Citations for anti-PPGB antibody

Galjart N.J., Cell 54:755-764(1988). Deloukas P., Nature 414:865-871(2001). Jackman H.L., J. Biol. Chem. 265:11265-11272(1990).

Other Notes

Small volumes of anti-PPGB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PPGB. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
lysosomal protective protein isoform a
NCBI Official Synonym Full Names
cathepsin A
NCBI Official Symbol
CTSA
NCBI Official Synonym Symbols
GSL; GLB2; NGBE; PPCA; PPGB
UniProt Protein Name
Lysosomal protective protein
UniProt Synonym Protein Names
Carboxypeptidase C; Carboxypeptidase L; Cathepsin A; Protective protein cathepsin A; PPCA
UniProt Gene Name
CTSA
UniProt Synonym Gene Names
PPGB; PPCA
NCBI Protein Information
lysosomal protective protein

NCBI Summary for PPGB

This gene encodes a member of the peptidase S10 family of serine carboxypeptidases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate two chains that comprise the heterodimeric active enzyme. This enzyme possesses deamidase, esterase and carboxypeptidase activities and acts as a scaffold in the lysosomal multienzyme complex. Mutations in this gene are associated with galactosialidosis. [provided by RefSeq, Nov 2015]
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UniProt Comments for PPGB

Protective protein appears to be essential for both the activity of beta-galactosidase and neuraminidase, it associates with these enzymes and exerts a protective function necessary for their stability and activity. This protein is also a carboxypeptidase and can deamidate tachykinins.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PPGB antibody

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