• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

5-HT-3A Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS851682

MBS851682 is an antibody targeting 5-HT-3A. Also known as 5-HT-3A Antibody. Reactive in Human. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
5-HT-3A, Antibody
Full Product Name
5-HT-3A Antibody
Product Gene Name
Product Synonym Names
5-HT-3; 5-HT3R; 5-hydroxytryptamine 3 receptor; 5HT3R; HTR3; HTR3A; serotonin-gated ion channel receptor
Species Reactivity
Human
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
5-HT-3A antibody detects endogenous levels of total 5-HT-3A protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
59,002 Da
OMIM
182139
3D Structure
ModBase 3D Structure for P46098
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human 5-HT-3A.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-5-HT-3A antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-5-HT-3A antibody
WB: 1:500-1:1000
ELISA: 1:1000

Western Blot (WB) of anti-5-HT-3A antibody

Western blot analysis of extracts from HT-29 cells, using 5-HT-3A antibody.
Anti-5-HT-3A Antibody – Cat# MBS851682

Product References and Citations for anti-5-HT-3A antibody

Miyake A., Mol. Pharmacol. 48:407-416(1995). Belelli D., Mol. Pharmacol. 48:1054-1062(1995). Yamada K., Biol. Psychiatry 60:192-201(2006).

Other Notes

Small volumes of anti-5-HT-3A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for 5-HT-3A. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
5-hydroxytryptamine receptor 3A isoform b
NCBI Official Synonym Full Names
5-hydroxytryptamine receptor 3A
NCBI Official Symbol
HTR3A
NCBI Official Synonym Symbols
HTR3; 5HT3R; 5-HT-3; 5-HT3A; 5-HT3R
UniProt Protein Name
5-hydroxytryptamine receptor 3A
UniProt Synonym Protein Names
5-hydroxytryptamine receptor 3; 5-HT-3; 5-HT3R; Serotonin receptor 3A; Serotonin-gated ion channel receptor
UniProt Gene Name
HTR3A
UniProt Synonym Gene Names
5HT3R; HTR3; 5-HT3-A; 5-HT3A; 5-HT-3; 5-HT3R
NCBI Protein Information
5-hydroxytryptamine receptor 3A

NCBI Summary for 5-HT-3A

The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Show more

UniProt Comments for 5-HT-3A

This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel.
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000