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MAGE-1 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS851740

MBS851740 is an antibody targeting MAGE-1. Also known as MAGE-1 Antibody. Reactive in Human. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MAGE-1, Antibody
Full Product Name
MAGE-1 Antibody
Product Gene Name
Product Synonym Names
MAGE1; MAGE1A; MZ2-E; melanoma-associated antigen 1
Species Reactivity
Human
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
MAGE-1 antibody detects endogenous levels of total MAGE-1 protein.
Preparation and Storage
Store at-20 degree C for 1 year
Molecular Weight
34,342 Da
OMIM
300016
3D Structure
ModBase 3D Structure for P43355
Immunogen
The antiserum was produced against synthesized peptide derived from human MAGE-1.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-MAGE-1 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-MAGE-1 antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:10000

Immunohistochemistry (IHC) of anti-MAGE-1 antibody

Peptide-+ Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using MAGE-1 antibody.
Anti-MAGE-1 Antibody – Cat# MBS851740

Western Blot (WB) of anti-MAGE-1 antibody

Western blot analysis of extracts from HepG2 cells, using MAGE-1 antibody.
Anti-MAGE-1 Antibody, Western Blot (WB) – Cat# MBS851740

Product References and Citations for anti-MAGE-1 antibody

J. Weber, Cancer Res., Apr 1994; 54: 1766-1771. DS Hoon, J. Immunol., Jan 1995; 154: 730. Gentao Liu, Cancer Res., Jul 2004; 64: 4980-4986. Charles De Smet, PNAS, Jul 1996; 93: 7149.

Other Notes

Small volumes of anti-MAGE-1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MAGE-1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
melanoma-associated antigen 1
NCBI Official Synonym Full Names
MAGE family member A1
NCBI Official Symbol
MAGEA1
NCBI Official Synonym Symbols
CT1.1; MAGE1
UniProt Protein Name
Melanoma-associated antigen 1
UniProt Synonym Protein Names
Antigen MZ2-E; Cancer/testis antigen 1.1; CT1.1; MAGE-1 antigen
UniProt Gene Name
MAGEA1
UniProt Synonym Gene Names
MAGE1; MAGE1A; CT1.1
NCBI Protein Information
melanoma-associated antigen 1

NCBI Summary for MAGE-1

This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. [provided by RefSeq, Jul 2008]
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UniProt Comments for MAGE-1

May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-MAGE-1 antibody

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