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ST14 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS851758

MBS851758 is an antibody targeting ST14. Also known as ST14 Antibody. Reactive in Human. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ST14, Antibody
Full Product Name
ST14 Antibody
Product Gene Name
Product Synonym Names
EC 3.4.21.109; HAI; MT-SP1; MTSP-1; MTSP1; PRSS14; SNC19; TADG-15; TADG15; matriptase; membrane-type serine protease 1; prostamin; serine protease TADG-15; suppressor of tumorigenicity 14; tumor associated differentially-expressed gene 15 protein
Species Reactivity
Human
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
ST14 antibody detects endogenous levels of total ST14 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
94,770 Da
OMIM
602400
3D Structure
ModBase 3D Structure for Q9Y5Y6
Immunogen
The antiserum was produced against synthesized peptide derived from N-terminal of human ST14.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-ST14 antibody
Western Blot (WB), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-ST14 antibody
WB: 1:500~1:1000
IF: 1:100~1:500
ELISA: 1:10000

Testing Data of anti-ST14 antibody

Anti-ST14 Antibody – Cat# MBS851758

Western Blot (WB) of anti-ST14 antibody

Peptide-+ Western blot analysis of extracts from A549 cells, using ST14 antibody. Immunofluorescence analysis of A549 cells, using ST14 antibody.
Anti-ST14 Antibody, Western Blot (WB) – Cat# MBS851758

Product References and Citations for anti-ST14 antibody

Lin C.Y., J. Biol. Chem. 274:18237-18242(1999). Bhatt A.S., Oncogene 24:5333-5343(2005). Ge W., J. Biol. Chem. 281:7406-7412(2006).

Other Notes

Small volumes of anti-ST14 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ST14. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
suppressor of tumorigenicity 14 protein
NCBI Official Synonym Full Names
suppression of tumorigenicity 14
NCBI Official Symbol
ST14
NCBI Official Synonym Symbols
HAI; MTSP1; SNC19; ARCI11; MT-SP1; PRSS14; TADG15; TMPRSS14
UniProt Protein Name
Suppressor of tumorigenicity 14 protein
UniProt Synonym Protein Names
Matriptase; Membrane-type serine protease 1; MT-SP1; Prostamin; Serine protease 14; Serine protease TADG-15; Tumor-associated differentially-expressed gene 15 protein
UniProt Gene Name
ST14
UniProt Synonym Gene Names
PRSS14; SNC19; TADG15; MT-SP1
NCBI Protein Information
suppressor of tumorigenicity 14 protein

NCBI Summary for ST14

The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis. [provided by RefSeq, Jul 2008]
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UniProt Comments for ST14

Degrades extracellular matrix. Proposed to play a role in breast cancer invasion and metastasis. Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site. Involved in the terminal differentiation of keratinocytes through prostasin (PRSS8) activation and filaggrin (FLG) processing.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ST14 antibody

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