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ELOVL6 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS851843

MBS851843 is an antibody targeting ELOVL6. Also known as ELOVL6 Antibody. Reactive in Human, Mouse, Rat. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ELOVL6, Antibody
Full Product Name
ELOVL6 Antibody
Product Gene Name
anti-ELOVL6 antibody
Product Synonym Names
Elongation of very long chain fatty acids protein 6; hELO2; Fatty acyl-CoA elongase; Long-chain fatty-acyl elongase
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
ELOVL6 antibody detects endogenous levels of total ELOVL6 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
31,376 Da
OMIM
611546
3D Structure
ModBase 3D Structure for Q9H5J4
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human ELOVL6.

Product Categories/Family for anti-ELOVL6 antibody

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-ELOVL6 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-ELOVL6 antibody
WB: 1:500-1:1000
ELISA: 1:10000

Western Blot (WB) of anti-ELOVL6 antibody

Western blot analysis of extracts from 293, HuvEc and K562 cells, using ELOVL6 antibody.
Anti-ELOVL6 Antibody – Cat# MBS851843

Product References and Citations for anti-ELOVL6 antibody

Sugano S., Nat. Genet. 36:40-45(2004). Wilson R.K., Nature 434:724-731(2005). The MGC Project Team, Genome Res. 14:2121-2127(2004).

Other Notes

Small volumes of anti-ELOVL6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ELOVL6. It may not necessarily be applicable to this product.

NCBI GI #
195539343
NCBI GeneID
79071
NCBI Accession #
NP_001124193.1
UniProt Primary Accession #
Q9H5J4
UniProt Secondary Accession #
Q4W5L0; Q8NCD1
UniProt Related Accession #
Q9H5J4
GenBank Nucleotide #
NM_001130721.1
NCBI Official Full Name
elongation of very long chain fatty acids protein 6
NCBI Official Synonym Full Names
ELOVL fatty acid elongase 6
NCBI Official Symbol
ELOVL6
NCBI Official Synonym Symbols
FAE; LCE; FACE
UniProt Protein Name
Elongation of very long chain fatty acids protein 6
UniProt Synonym Protein Names
3-keto acyl-CoA synthase ELOVL6
UniProt Gene Name
ELOVL6
UniProt Synonym Gene Names
ELOVL FA elongase 6; hELO2
NCBI Protein Information
elongation of very long chain fatty acids protein 6

NCBI Summary for ELOVL6

Fatty acid elongases (EC 6.2.1.3), such as ELOVL6, use malonyl-CoA as a 2-carbon donor in the first and rate-limiting step of fatty acid elongation (Moon et al., 2001 [PubMed 11567032]).[supplied by OMIM, Mar 2008]

UniProt Comments for ELOVL6

Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate in the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
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Research Articles on ELOVL6

1. Functional screening...revealed ELOVL6 as the main elongation enzyme responsible for acyl chain elongation in lung cancer squamous cell carcinoma cancer cells

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-ELOVL6 antibody

 Products by Pathway  Pathway Diagram
 Activation Of Gene Expression By SREBP (SREBF) Pathway antibodies  Activation Of Gene Expression By SREBP (SREBF) Pathway Diagram
 Biosynthesis Of Unsaturated Fatty Acids Pathway antibodies  Biosynthesis Of Unsaturated Fatty Acids Pathway Diagram
 Biosynthesis Of Unsaturated Fatty Acids Pathway antibodies  Biosynthesis Of Unsaturated Fatty Acids Pathway Diagram
 Fatty Acyl-CoA Biosynthesis Pathway antibodies  Fatty Acyl-CoA Biosynthesis Pathway Diagram
 Fatty Acid Biosynthesis, Elongation, Endoplasmic Reticulum Pathway antibodies  Fatty Acid Biosynthesis, Elongation, Endoplasmic Reticulum Pathway Diagram
 Fatty Acid Biosynthesis, Elongation, Endoplasmic Reticulum Pathway antibodies  Fatty Acid Biosynthesis, Elongation, Endoplasmic Reticulum Pathway Diagram
 Fatty Acid Elongation Pathway antibodies  Fatty Acid Elongation Pathway Diagram
 Fatty Acid Elongation Pathway antibodies  Fatty Acid Elongation Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram

Diseases associated with anti-ELOVL6 antibody

 Disease Name  Pubmed Publications
 Fatty Liver Antibodies  >27 publications with ELOVL6 and Fatty Liver
 Insulin Resistance Antibodies  >16 publications with ELOVL6 and Insulin Resistance
 Liver Diseases Antibodies  >9 publications with ELOVL6 and Liver Diseases
 Inflammation Antibodies  >7 publications with ELOVL6 and Inflammation
 Non-alcoholic Fatty Liver Disease Antibodies  >4 publications with ELOVL6 and Non-alcoholic Fatty Liver Disease
 Hyperglycemia Antibodies  >4 publications with ELOVL6 and Hyperglycemia
 Fibrosis Antibodies  >3 publications with ELOVL6 and Fibrosis
 Neoplasms Antibodies  >3 publications with ELOVL6 and Neoplasms
 Hypertriglyceridemia Antibodies  >3 publications with ELOVL6 and Hypertriglyceridemia
 Cardiovascular Diseases Antibodies  >3 publications with ELOVL6 and Cardiovascular Diseases

Organs/Tissues associated with anti-ELOVL6 antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >29 publications with ELOVL6 and Liver
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