• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

HEY2 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS851847

MBS851847 is an antibody targeting HEY2. Also known as HEY2 Antibody. Reactive in Human, Mouse. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
HEY2, Antibody
Full Product Name
HEY2 Antibody
Product Gene Name
Product Synonym Names
Hairy/enhancer-of-split related with YRPW motif protein 2; Cardiovascular helix-loop-helix factor 1; hCHF1; Hairy and enhancer of split-related protein 2; HESR-2; Hairy-related transcription factor 2; hHRT2; HES-related repressor protein 2; Protein gridlock homolog; HEY2; CHF1; GRL; HERP; HERP1; HRT2
Species Reactivity
Human, Mouse
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
HEY2 antibody detects endogenous levels of total HEY2 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
35,808 Da
OMIM
604674
3D Structure
ModBase 3D Structure for Q9UBP5
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human HEY2.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-HEY2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-HEY2 antibody
WB: 1:500-1:1000
ELISA: 1:1000

Western Blot (WB) of anti-HEY2 antibody

Western blot analysis of extracts from K562 cells, using HEY2 antibody.
Anti-HEY2 Antibody – Cat# MBS851847

Product References and Citations for anti-HEY2 antibody

Chin M.T., J. Biol. Chem. 275:6381-6387(2000). Nakagawa O., Proc. Natl. Acad. Sci. U.S.A. 97:13655-13660(2000). Iso T., Mol. Cell. Biol. 21:6071-6079(2001).

Other Notes

Small volumes of anti-HEY2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for HEY2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
hairy/enhancer-of-split related with YRPW motif protein 2
NCBI Official Synonym Full Names
hes related family bHLH transcription factor with YRPW motif 2
NCBI Official Symbol
HEY2
NCBI Official Synonym Symbols
GRL; CHF1; HRT2; HERP1; HESR2; bHLHb32; GRIDLOCK
UniProt Protein Name
Hairy/enhancer-of-split related with YRPW motif protein 2
UniProt Synonym Protein Names
Cardiovascular helix-loop-helix factor 1; hCHF1; Class B basic helix-loop-helix protein 32; bHLHb32; HES-related repressor protein 2; Hairy and enhancer of split-related protein 2; HESR-2; Hairy-related transcription factor 2; HRT-2; hHRT2; Protein gridlock homolog
UniProt Gene Name
HEY2
UniProt Synonym Gene Names
BHLHB32; CHF1; GRL; HERP; HERP1; HRT2; hCHF1; bHLHb32; HESR-2; HRT-2; hHRT2
NCBI Protein Information
hairy/enhancer-of-split related with YRPW motif protein 2

NCBI Summary for HEY2

This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The encoded protein forms homo- or hetero-dimers that localize to the nucleus and interact with a histone deacetylase complex to repress transcription. Expression of this gene is induced by the Notch signal transduction pathway. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternatively spliced transcript variants have been found, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Show more

UniProt Comments for HEY2

Downstream effector of Notch signaling which may be required for cardiovascular development. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000