• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

GPRC5B Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS851939

MBS851939 is an antibody targeting GPRC5B. Also known as GPRC5B Antibody. Reactive in Human. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GPRC5B, Antibody
Full Product Name
GPRC5B Antibody
Product Gene Name
anti-GPRC5B antibody
Product Synonym Names
G protein-coupled receptor; family C; group 1; member B; G protein-coupled receptor; family C; group 5; member B; G-protein coupled receptor family C group 5 member B; GPC5B; RAIG-2; RAIG2; retinoic acid responsive gene protein; retinoic acid-induced gene 2 protein
Species Reactivity
Human
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
GPRC5B antibody detects endogenous levels of total GPRC5B protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
44,933 Da
OMIM
605948
3D Structure
ModBase 3D Structure for Q9NZH0
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human GPRC5B.

Product Categories/Family for anti-GPRC5B antibody

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-GPRC5B antibody
Western Blot (WB), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-GPRC5B antibody
WB: 1:500~1:1000
IF: 1:100~1:500
ELISA: 1:1000

Testing Data of anti-GPRC5B antibody

Anti-GPRC5B Antibody – Cat# MBS851939

Western Blot (WB) of anti-GPRC5B antibody

Peptide-+ Western blot analysis of extracts from HUVEC cells, 293cells and Jurkat cells, using GPRC5B antibody. Immunofluorescence analysis of MCF-7 cells, using GPRC5B antibody.
Anti-GPRC5B Antibody, Western Blot (WB) – Cat# MBS851939

Product References and Citations for anti-GPRC5B antibody

Braeuner-Osborne H., Genomics 65:121-128(2000). Robbins M.J., Genomics 67:8-18(2000). Ota T., Nat. Genet. 36:40-45(2004).

Other Notes

Small volumes of anti-GPRC5B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GPRC5B. It may not necessarily be applicable to this product.

NCBI GI #
7706451
NCBI GeneID
51704
NCBI Accession #
NP_057319.1
UniProt Primary Accession #
Q9NZH0
UniProt Secondary Accession #
O75205; Q8NBZ8; D2DFB0
UniProt Related Accession #
Q9NZH0
GenBank Nucleotide #
NM_016235.2
NCBI Official Full Name
G-protein coupled receptor family C group 5 member B isoform 1
NCBI Official Synonym Full Names
G protein-coupled receptor class C group 5 member B
NCBI Official Symbol
GPRC5B
NCBI Official Synonym Symbols
RAIG2; RAIG-2
UniProt Protein Name
G-protein coupled receptor family C group 5 member B
UniProt Synonym Protein Names
A-69G12.1; Retinoic acid-induced gene 2 protein; RAIG-2
Protein Family
G-protein coupled receptor family
UniProt Gene Name
GPRC5B
UniProt Synonym Gene Names
RAIG2; RAIG-2
NCBI Protein Information
G-protein coupled receptor family C group 5 member B

NCBI Summary for GPRC5B

This gene encodes a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The encoded protein may modulate insulin secretion and increased protein expression is associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]
Show more

UniProt Comments for GPRC5B

Unknown. This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways.CautionIt is uncertain whether Met-1 or Met-9 is the initiator.

Research Articles on GPRC5B

1. this study proposes that increased expression of GPRC5B contributes to the reduced insulin secretion and beta-cell viability observed in type-2 diabetes.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-GPRC5B antibody

 Products by Pathway  Pathway Diagram
 GPCRs, Class C Metabotropic Glutamate, Pheromone Pathway antibodies  GPCRs, Class C Metabotropic Glutamate, Pheromone Pathway Diagram

Diseases associated with anti-GPRC5B antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >1 publications with GPRC5B and Inflammation

Organs/Tissues associated with anti-GPRC5B antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >8 publications with GPRC5B and Brain
 Pancreas Antibodies  >2 publications with GPRC5B and Pancreas
 Kidney Antibodies  >2 publications with GPRC5B and Kidney
 Intestine Antibodies  >1 publications with GPRC5B and Intestine
 Vascular Antibodies  >1 publications with GPRC5B and Vascular
 Heart Antibodies  >1 publications with GPRC5B and Heart
 Placenta Antibodies  >1 publications with GPRC5B and Placenta
 Lung Antibodies  >1 publications with GPRC5B and Lung
 Embryonic Tissue Antibodies  >1 publications with GPRC5B and Embryonic Tissue
 Prostate Antibodies  >1 publications with GPRC5B and Prostate
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000