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Claudin 3 (CLDN3) Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS851948

MBS851948 is an antibody targeting CLDN3. Also known as Claudin 3 (Ab-219) Antibody. Reactive in Human. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Claudin 3 (CLDN3), Antibody
Full Product Name
Claudin 3 (Ab-219) Antibody
Product Gene Name
Product Synonym Names
CLD3; Clostridium perfringens enterotoxin receptor 2; CPE-R 2; CPE-receptor 2; HRVP1; Ventral prostate 1 protein homolog
Species Reactivity
Human
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
Claudin 3 (Ab-219) antibody detects endogenous levels of total Claudin 3 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
23,319 Da
OMIM
602910
3D Structure
ModBase 3D Structure for O15551
Immunogen
The antiserum was produced against synthesized non-phosphopeptide derived from human Claudin 3 around the phosphorylation site of tyrosine 219 (R-K-D-YP-V).
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CLDN3 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-CLDN3 antibody
WB: 1:500-1:1000
ELISA: 1:1000

Western Blot (WB) of anti-CLDN3 antibody

Western blot analysis of extracts from COLO cells, treated with EGF (200ng/ml, 30mins), using Claudin 3 (Ab-219) antibody.
Anti-CLDN3 Antibody – Cat# MBS851948

Product References and Citations for anti-CLDN3 antibody

Peacock R.E., Genomics 46:443-449(1997). Katahira J., J. Biol. Chem. 272:26652-26658(1997). The MGC Project Team; Genome Res. 14:2121-2127(2004).

Other Notes

Small volumes of anti-CLDN3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CLDN3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
claudin-3
NCBI Official Synonym Full Names
claudin 3
NCBI Official Symbol
CLDN3
NCBI Official Synonym Symbols
RVP1; HRVP1; C7orf1; CPE-R2; CPETR2
UniProt Protein Name
Claudin-3
UniProt Synonym Protein Names
Clostridium perfringens enterotoxin receptor 2; CPE-R 2; CPE-receptor 2; Rat ventral prostate.1 protein homolog; hRVP1
Protein Family
UniProt Gene Name
CLDN3
UniProt Synonym Gene Names
C7orf1; CPETR2; CPE-R 2; CPE-receptor 2; hRVP1
NCBI Protein Information
claudin-3

NCBI Summary for CLDN3

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat. [provided by RefSeq, Jul 2008]
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UniProt Comments for CLDN3

Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CLDN3 antibody

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